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Author Topic: Curing Hep C Tied to Improvement in Insulin Resistance  (Read 7047 times)

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Offline Hep Editors

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Curing Hep C Tied to Improvement in Insulin Resistance
« on: June 17, 2020, 10:25:04 am »
Curing hepatitis C virus (HCV) through direct-acting antiviral (DAA) treatment is associated with improvements in insulin resistance, although less so for people with a higher body mass index (BMI).

Francisco Paolo Russo, MD, of Padua University Hospital in Italy, and colleagues conducted a prospective study of 138 people with HCV who were treated with DAAs at three Italian health care centers between May 2015 and December 2016. The study excluded people with diabetes.

The study authors defined insulin resistance as having a homeostasis model assessment index for insulin resistance (HOMA-IR) score greater than 2.5. The participants received FibroScan tests of their liver to assess for cirrhosis when they started DAAs and at 24 and 48 weeks after they finished treatment for HCV.

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