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Author Topic: Vosevi  (Read 13604 times)

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Offline PaulG

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  • Posts: 38
Vosevi
« on: January 15, 2021, 01:47:10 pm »
 Just started treatment today using Vosevi who else has used Vosevi

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Vosevi
« Reply #1 on: January 16, 2021, 05:18:15 am »
Hi Paul it’s been kinda quiet around here since the new meds became available starting in 2014 and so many of us are now cured. I treated with Harvoni. Hopefully someone will chime in who did treat with Vosevi. You could try searching the forum for posts about Vosevi so see what others experienced.

But anyway just wanted to bid you welcome and best of luck on your journey
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Lynn K

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  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Vosevi
« Reply #2 on: January 16, 2021, 05:24:48 am »
Ok just read your old posts I see you were around back a few years ago and relapsed after treating with Harvoni

Best of luck on this your round two of your fight against the dragon
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline PaulG

  • Member
  • Posts: 38
Re: Vosevi
« Reply #3 on: January 16, 2021, 01:21:55 pm »
Thanks for the reply. Yes I was treated with 8 weeks of Harvoni and never got to undetectable, so not sure I'd call it relapse lol. First day day on Vosevi and no side effects at all, hope this continues this way. Take care be safe

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Vosevi
« Reply #4 on: January 16, 2021, 11:58:13 pm »
Ok yeah guess that would make you a non responder then

Well the newest treatments are even more effective than the earlier ones so best of luck and kick the dragons butt this time
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline PaulG

  • Member
  • Posts: 38
Re: Vosevi
« Reply #5 on: January 17, 2021, 12:26:53 am »
I do have more faith in this one, with the 8 week Harvoni treatment  I was approved for 12 weeks but doctor thought 8 week . Long story but wasn't  a happy camper and thought the doctor was more into seeing if the  8 week would work and not what was best for me. I'll beat it this time

Offline PaulG

  • Member
  • Posts: 38
Re: Vosevi
« Reply #6 on: February 08, 2021, 07:59:37 pm »
3 weeks of treatment AST   29 U/L (ALT)   26 U/L HCV RNA, QUANTITATIVE REAL TIME PCR   <15 DETECTED IU/mL HCV RNA VIRAL LOAD LOG RESULT   <1.18 DETECTED LogIU/mL

Offline Lynn K

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  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Vosevi
« Reply #7 on: February 08, 2021, 09:20:52 pm »
Looking good fingers crossed
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline PaulG

  • Member
  • Posts: 38
Re: Vosevi
« Reply #8 on: July 07, 2021, 11:33:56 pm »
Cured no sign of the virus

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Vosevi
« Reply #9 on: July 07, 2021, 11:53:58 pm »
Hey thanks so much for the update! Congrats on your results and enjoy your new hep c free life!

:)
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline PaulG

  • Member
  • Posts: 38
Re: Vosevi
« Reply #10 on: July 08, 2021, 12:08:55 am »
Thanks and should also say Vosevi was easy 12 weeks

Offline northfork

  • Member
  • Posts: 57
Re: Vosevi
« Reply #11 on: July 10, 2021, 11:25:58 pm »
Yes, I relapsed after 24 weeks on Harvoni, but Vosevi did the trick.

Probably infected 1969. Diagnosed 2006. Genotype 1b.
Daclatasvir/ Asunaprevir 2013:relapse
Harvoni 24 weeks 2015:relapse
sofosbuvir, velpatisvir, voxillaprevir  trial started on drug 7/16. Viral load 890,000 approx. F2. Undetected after week 1.
12 week SVR achieved Jan 2017.
SVR 24 achieved April 2017 !

60 weeks post treatment...UNDETECTED!

Offline gr8inTx

  • Newbie
  • Posts: 1
Re: Vosevi
« Reply #12 on: July 28, 2021, 04:18:38 pm »
Hi from Texas.  I have 12 days left of vosevi.  i completed Mayvrett 2 years ago and relapsed.  Undetectable right now with the vosevi.  I have done pretty good with it other than the extreme fatigue...  i just push through and look at the light at the end of the tunnell.  God bless you all and good luck!!  #wedorecover

Offline jberlin

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  • Member
  • Posts: 319
  • Contracted Hep C in 76, treated 2004 & 2012, cured
Re: Vosevi
« Reply #13 on: September 01, 2021, 02:45:45 pm »
Please update us at 3 months post this current treatment as to what we hope and predict will be undetectable! -jack

Offline Lynn K

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  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Vosevi
« Reply #14 on: September 01, 2021, 03:17:28 pm »
Hi gr8in Tx

I treated a total of 5 times. Three with the old interferon based regimens. I was a null responder to those no change in viral load.

When the new DAA’s were first approved I treated with Sovaldi and Olysio off label usage for 12 weeks but I was found to have relapsed 12 weeks after finishing treatment. Then Harvoni was approved in October 2014. My Dr prescribed me 24 weeks of Harvoni with Ribavirin. That was my last treatment I was finally cured.

Long way of saying if I can be cured I’m very confident you will be too. As Jack says please check back and let us know your 12 weeks post treatment results that’s the one for all the marbles!

Good luck!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

 


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