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Author Topic: All these abbreviations in the forums has me stumped!  (Read 9266 times)

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Offline Elfbeans

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  • Posts: 6
All these abbreviations in the forums has me stumped!
« on: January 21, 2015, 09:14:58 am »
Is there a Sticky that explains the acronyms and abbreviations? I am waiting for prescription approval and have not started any treatment yet, but I am reading as much as I can here. The information is invaluable to me. But the shorthand here has me scratching my head! Help? :-)

Offline Amj1951

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  • Posts: 118
Re: All these abbreviations in the forums has me stumped!
« Reply #1 on: January 21, 2015, 10:15:53 am »
Hi Elfbeans, It takes a while to figure it all out but don't despair : ) I really don't get it all, but as you 'see it' more often it starts making sense and someone will come along who has more of a idea and list.. I hope. I find for me, just reading thru some of the topics.. it starts making more sense.

I know VL is viral load and that is the number you want to get to 0.. which means ... I am pretty sure the SVR is your cleared of the Hep C or are clearing it.

Genotype is like 1 2 3 etc.. I am genotype 1a. Your doctor can tell you yours and should have if your waiting on the meds?

I have seen S/O which I THINK is another type of treatment some are on... and I am going to stop there because if I have this wrong.. someone can correct me so I don't totally mess it up for you and look like a complete idiot in the process  : )

I am on day 15 of Harvoni and I am still learning, but I am so glad I found this forum because there are some great people here... and a lot of really good information.

Good luck on your treatment! : )
Meredith
« Last Edit: January 21, 2015, 10:18:05 am by Amj1951 »

Offline Red Hen

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  • Posts: 187
Re: All these abbreviations in the forums has me stumped!
« Reply #2 on: January 21, 2015, 11:43:16 am »
Hi, Elfbeans and Amj1951. Glad I'm not the only one who gets confused with all the abbreviations!
genotype 1a
completed 12 weeks Viekira pak and ribavirin
final results due around the end of April
Undetected 12 weeks post treatment!

Offline Elfbeans

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  • Posts: 6
Re: All these abbreviations in the forums has me stumped!
« Reply #3 on: January 21, 2015, 02:10:10 pm »
Hi Amj1951 Thanks! Yes, my doctor has informed me I am genotype 2b. And yeah, 'SVR' is one I don't understand. I figured out VL (mine is 6693834 I guess... I can access my labs online thru my family doctor site. Now I am seeing a hepatologist I don't think that benefit is available.) I think 'tx' is treatment? I can't remember what else I was reading here last night that I didn't understand...
Perhaps we can ask that occasionally folks would type out in full what they mean, every once in a while?
Meanwhile, I wait for a yea or a nay....

Offline Mike

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  • Posts: 999
Re: All these abbreviations in the forums has me stumped!
« Reply #4 on: January 21, 2015, 03:48:16 pm »
EOT = end of treatment

VR   = virological response

VL = viral load

SVR = sustained virological response. This is the period after treatment ends, hence "sustained. An SVR4 means no virus present 4 weeks after treatment has ended. SVR12 means no virus present 12 weeks after treatment ended and so on.

tx = treatment

hx = history

UND = undetected viral load

S/O = Sovaldi and Olysio

HCV = Hepatitis C Virus

PCR = Polymerase chain reaction

RNA = Ribonucleic acid

ALT  = Alanine aminotransferase

AST  = Aspartate aminotransferase

DX = diagnosis

CBC = complete blood count

Best wishes, Mike
« Last Edit: January 21, 2015, 03:58:28 pm by Mike »
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline Elfbeans

  • Member
  • Posts: 6
Re: All these abbreviations in the forums has me stumped!
« Reply #5 on: January 21, 2015, 04:06:53 pm »
Mike! THANKS! ;D

Offline Amj1951

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  • Posts: 118
Re: All these abbreviations in the forums has me stumped!
« Reply #6 on: January 21, 2015, 07:40:10 pm »
Thank you Mike!!

Offline Red Hen

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  • Posts: 187
Re: All these abbreviations in the forums has me stumped!
« Reply #7 on: January 21, 2015, 08:12:19 pm »
Thank you, Mike!
genotype 1a
completed 12 weeks Viekira pak and ribavirin
final results due around the end of April
Undetected 12 weeks post treatment!

Offline Lynn K

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  • Member
  • Posts: 4,546
  • Get tested, get treated, get cured, fight Hep c!
Re: All these abbreviations in the forums has me stumped!
« Reply #8 on: January 21, 2015, 11:25:26 pm »
Thanks Mike I have an even longer list for those who enjoy lists

Hepatitis C Acronyms/Abbreviations
Hepatitis C Acronyms and some Definitions:
 
 
HCV - Hep C : Hepatitis C virus
Boceprevir: Victrelis
Teleprevir: Incevik
Inf: Interferon

GS-7977 Experimental drug by Gilead Sciences Inc. Phase 3 trials underway in conjunction with Rbv

Riba/Rbv: Ribavirin
Bx: Biopsy : Invasive liver sample removed and analized to determine liver condition
Fibroscan: Non invasive Ultrasound Technique for determining liver condition
Fibrosure/Fibrotest: Combination of blood test scores used for determining liver condition
Dx: Diagnosis
GT: Genotype
IR: Insulin Resistant
IL28B: A gene polymorphism which helps in Tx prediction -  CC , CT , TT
Sx: Side effects
Tx : Treatment
 
SOT: Start of Treatment
EOT: End of Treatment
RVR: Rapid viral response - Undetected virus at 4 wks. Tx
cEVR: Complete Early Viral Response: PCR Und at Week 12 (P/R Tx)
EVR: Early Virological Response:  >2 Log Drop at Wk. 12
eRVR - Extended Rapid Viral Response - Und virus @ Wk.4 - Wk. 12
Und : Undetected virus
SVR: Sustained Viral Response: Und after 6 months EOT
P/R Tx: Pegelated Interferon / Ribaviron Treatment (old term - SOC: standard of care)
VL: Viral Load - amount of virons per IU (International Unit)
IU: International Unit (1 IU = 2.5 VL Copies apx )
HVL: High Viral Load (≥800,000 IU)
LVL: Low viral load (<800,000 IU)

PCR: Polymerase Chain Reaction
RT-PCR quantitative: using Reverse Transcription-Polymerase Chain Reaction- to count how many virus are in blood

RT-PCR qualitative: a "positive" or "negative" using Reverse
Transcription-Polymerase Chain Reaction to see if there are at least 50 IU/mlviruses detected in bloodRNA: RiboNucleic Acid
Rx: Prescription
TMA: Transcription Mediated Amplification
All oral Tx: Interferon-free treatment (Phase 2 Clinical Trials)
 
More Acronyms:
 
AFP: Alpha-FetoProtein
ALP: Alkaline Phosphatase (Alk Phos)
ALT/SGPT: Alanine Aminotransferase - liver function blood test
AST/SGOT: Aspartate Aminotransferase - liver function blood test
CBC: Complete Blood Count
DAA: Direct Acting Anti-viral
ELISA: Enzyme-Linked ImmunoSorbent Assay
EPO: Erythropoietin Epoetin alfa (Epogen/Procrit), Darbepoetin alfa (Aranesp)
ESA:: Erythropoiesis Stimulating Agent
ESLD: End-Stage Liver Disease
GGT:: Gamma Glutamyl Transpeptidase
HCC: HepatoCellular Carcinoma (Liver Cancer)
HDL: High Density Lipoproteins (Good Cholesterol)
HGB: Hemoglobin
IFN: Interferon (Alpha 2a/2b)
IU: International Unit 1 IU (2.5 VL Copies apx)
LDL: Low Density Lipoproteins (Bad Cholesterol)
LFT: Liver Function Test
LLN: Lower Limit of Normal
NAFLD: Non Alcoholic Fatty Liver Disease (Steatosis)
NASH: Non Alcoholic SteatoHepatitis
Neup: Neupogen
PEG: PolyEthylene Glycol
PegIFN: Pegylated Interferon Alpha (2a/2b)
PI : Protease Inhibitor
RBC: Red Blood Cell Count
RIBA: Recombinant ImmunoBlot Assay
TMA: Transcription Mediated Amplification
TSH: Thyroid stimulating hormone or Thyrotropin
ULN: Upper Limit of Normal
VLDL: Very Low Density Lipoproteins
WBC: White Blood Cell Count
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Red Hen

  • Member
  • Posts: 187
Re: All these abbreviations in the forums has me stumped!
« Reply #9 on: January 22, 2015, 11:45:24 am »
Lynn, That's great! Guess I'll look 'em up as I come across 'em.  ;D
genotype 1a
completed 12 weeks Viekira pak and ribavirin
final results due around the end of April
Undetected 12 weeks post treatment!

 


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