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Author Topic: Lab Results  (Read 17160 times)

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Offline gug

  • Member
  • Posts: 15
Lab Results
« on: March 17, 2015, 09:42:59 am »
I started Harvoni on 1/30/2015. 12 week regimen in day 45 of 84. Am I headed in a good direction? I have been reading here and learning. So Thanks in advance for your replies. The following are my results:

ALT pre treatment 207       3/16/15 ALT 87
AST pre treatment 96         3/16/15 AST 52

HCV result (LOG)  4/8/2014 7.66 2/27/2015 <1.18

HCV results (IU)   4/8/2014 46041982  2/27/2015  HCV/RNA Detected Less than 15 iu/ml

« Last Edit: March 17, 2015, 09:56:25 am by gug »

Offline Mike

  • Member
  • Posts: 999
Re: Lab Results
« Reply #1 on: March 17, 2015, 02:38:07 pm »
Hey Gug,

Those are great results. Congrats!

Best wishes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #2 on: March 17, 2015, 03:17:43 pm »
Hey Gug,

Those are great results. Congrats!

Best wishes, Mike

Thanks Mike. I wasn't to sure on the ALT/AST but the rest seemed good.

Offline DisabledHepcat

  • Member
  • Posts: 44
Re: Lab Results
« Reply #3 on: March 17, 2015, 03:39:07 pm »
Am I reading that right? you had a virus count of 46 million?
Mine was only 1.2 million.
If so, you have become the spokesperson on how well Harvoni works.
As long as you don't have cirrhosis (parts of your liver that have turned into shoe leather) The liver can rebuild itself pretty quick with a good diet.
Like getting a self made liver transplant.

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #4 on: March 17, 2015, 04:09:41 pm »
Am I reading that right? you had a virus count of 46 million?
Mine was only 1.2 million.
If so, you have become the spokesperson on how well Harvoni works.
As long as you don't have cirrhosis (parts of your liver that have turned into shoe leather) The liver can rebuild itself pretty quick with a good diet.
Like getting a self made liver transplant.

Not sure how to insert an image but I have it on scan. It was 46041982, now less than 15. No cirrhosis or scarring.
« Last Edit: March 17, 2015, 04:13:35 pm by gug »

Offline motor

  • Member
  • Posts: 58
Re: Lab Results
« Reply #5 on: March 17, 2015, 04:14:19 pm »
 Hey GUG, my GI doctor explained to me that elevated ALT and AST numbers indicate liver inflammation.  So, I take it those numbers decreasing is good.
   But, I'm curious if you were told the range for normal.  I get access to all my blood- work reports and they always show the range for normal, which is not a constant.  For example:  2010  ALT 60(17-63)  normal   AST 44(15-41) 12% High
                   2013  ALT 77(0-44)  75% H     AST 57(0-40)  43% High
   I never see any ALT or AST posts with range or expressed as percentage.  I'm confused by these posts.  From above the ALT 60 normal would be 36% High with 2013 range.
   I can't even muster a question for HCV results, just hope for UND, the rest confusing.     
   
Age 66male GT 1a/CT  Dx 5/19/14
Likely infected early 70's
VL 3.7mil FibroScan F2 FSure F2
ALT 84(12-78) AST 56(3-36) High
Tx naive
8wks Harvoni start 3/3/15 VA
4wks ALT 25(12-78) AST 22(3-36) Normal 
        VL  <15  NOT DETECTED
8wks ALT 24 AST 19 
EOT  VL   <15  NOT DETECTED
SVR12 VL <15  NOT DETECTED

Offline Mike2

  • Member
  • Posts: 14
Re: Lab Results
« Reply #6 on: March 17, 2015, 04:42:18 pm »
Hi,
Let me know your thoughts? Just got my 3 1/2wk lab results
I'm currently approved for 8wk treatment but appealing for 12wks.
Here goes the results:
AST-normal
ALt- normal
VL- 12 detected
Going next week to check VL again hoping it's negative.
Started Harvoni 2/16/15
Treatment naive
VL was 2,500,000

Offline kauri

  • Member
  • Posts: 21
Re: Lab Results
« Reply #7 on: March 17, 2015, 06:21:34 pm »
Hi Mike2,

I don't have any specialized knowledge, but I read that if the viral load is less than 15, that counts as cleared. That might not be the exact number, but I believe your result is going to count as successful clearance. Does anyone else know if that is correct?
Do you, or anyone else, know what would happen if they give you only 8 weeks and you relapse?


Kauri
GT !a, likely infected '77 or '83 (needle or tattoo)
DX '95
'95 Interferon stopped bec. low white blood cell count
Fibrosis: F3MANY
Necroinflamm: A3SEV
Viral load at beginning of treatment: 27 million copies or 10.3 million IU/mL
HARVONI begun: March 17, 2015 12 week course

Offline Mike2

  • Member
  • Posts: 14
Re: Lab Results
« Reply #8 on: March 17, 2015, 06:53:45 pm »
Hi Kauri,
    Harvoni is really a walk in the park compared to your past treatments.
As far as my treatment is concerned my Nurse Practitioner is appealing the insurance company for the additional 4wks. Good luck to you and may you have an easy treatment.

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #9 on: March 17, 2015, 07:58:23 pm »
Hey GUG, my GI doctor explained to me that elevated ALT and AST numbers indicate liver inflammation.  So, I take it those numbers decreasing is good.
   But, I'm curious if you were told the range for normal.  I get access to all my blood- work reports and they always show the range for normal, which is not a constant.  For example:  2010  ALT 60(17-63)  normal   AST 44(15-41) 12% High
                   2013  ALT 77(0-44)  75% H     AST 57(0-40)  43% High
   I never see any ALT or AST posts with range or expressed as percentage.  I'm confused by these posts.  From above the ALT 60 normal would be 36% High with 2013 range.
   I can't even muster a question for HCV results, just hope for UND, the rest confusing.     
 

My Chart shows ALT <78 and AST <35. So that is what I am shooting for.

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #10 on: March 19, 2015, 05:52:46 am »

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #11 on: March 31, 2015, 09:35:34 am »
Updated Lab Results. As of my 8 week labs, HCV/RNA Not Detected.

Offline motor

  • Member
  • Posts: 58
Re: Lab Results
« Reply #12 on: March 31, 2015, 11:40:20 am »
Great news gug thx for posting
Age 66male GT 1a/CT  Dx 5/19/14
Likely infected early 70's
VL 3.7mil FibroScan F2 FSure F2
ALT 84(12-78) AST 56(3-36) High
Tx naive
8wks Harvoni start 3/3/15 VA
4wks ALT 25(12-78) AST 22(3-36) Normal 
        VL  <15  NOT DETECTED
8wks ALT 24 AST 19 
EOT  VL   <15  NOT DETECTED
SVR12 VL <15  NOT DETECTED

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #13 on: March 31, 2015, 12:39:09 pm »
Thank You!

Offline Long_Haul

  • Member
  • Posts: 161
  • Slayed the Dragon
Re: Lab Results
« Reply #14 on: March 31, 2015, 02:41:43 pm »
Great news GUG, doing a happy dance for you. I just got my EOT results Undetected, now I wait for SVR12 and being cured.

Great job you are doing keeping on the program, keep it up and you will be free of the beast!

Best wishes,

AL
Genotype 1A

Diagnosed 1989
Biopsy-cirrhosis stage 4 2000, no starting VL this round

3 rounds of Int+Rib
(Combo/48wks,Peg/26 Wks,Triple with Incivek/16wks)
UND with Incivek, Relapsed
Started 12 weeks Harvoni and Rib Jan 2nd,2015
4 weeks Undetected
8 weeks Undetected!
EOT at 12 weeks Undetected
EOT at 24 weeks STILL UNDETECTED
Completed TX Mar 26th,2015

EOT plus 4 weeks UNDETECTED
EOT plus 12 weeks UNDETECTED !!!!!!!!!!! I am DONE!

NO LONGER a member of the "WAITING GANG"

Offline Ledoc01

  • Member
  • Posts: 37
Re: Lab Results
« Reply #15 on: March 31, 2015, 07:45:55 pm »
@gug

great news...congratulations.

Mine was detected <12 @ 4 weeks. I'm just past week 5 now.
I'm calling me "cautiously optimistic" but my gut says it'll be just fine.

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #16 on: April 15, 2015, 05:50:58 am »
@gug

great news...congratulations.

Mine was detected <12 @ 4 weeks. I'm just past week 5 now.
I'm calling me "cautiously optimistic" but my gut says it'll be just fine.

I would say so  :)

Offline gug

  • Member
  • Posts: 15
Re: Lab Results
« Reply #17 on: May 19, 2015, 09:14:06 am »
I wanted to provide an update of my progress.

The week 8 and 12 both came back as undetected. A Fibroscan was done and there is some fibrosis, between F1-2. My Hepatologist says this will heal itself as the HCV is not active.

I consider myself blessed being I started out with a VL of 46041982. So at this point this stuff clearly works.

Offline motor

  • Member
  • Posts: 58
Re: Lab Results
« Reply #18 on: May 19, 2015, 10:18:13 am »
Good to hear GUG, I asked my GI doc about another FibroScan and he wants to wait a year, said liver takes 1-3yrs to heal itself.
  Your 46M VL is highest I've seen posted, but I talked to friend of friend who told me her count was up to 70M.
   How lucky we are to have Harvoni become available to us.
Age 66male GT 1a/CT  Dx 5/19/14
Likely infected early 70's
VL 3.7mil FibroScan F2 FSure F2
ALT 84(12-78) AST 56(3-36) High
Tx naive
8wks Harvoni start 3/3/15 VA
4wks ALT 25(12-78) AST 22(3-36) Normal 
        VL  <15  NOT DETECTED
8wks ALT 24 AST 19 
EOT  VL   <15  NOT DETECTED
SVR12 VL <15  NOT DETECTED

Offline Mike

  • Member
  • Posts: 999
Re: Lab Results
« Reply #19 on: May 19, 2015, 12:45:40 pm »
Great news, Gug!

Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

 


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