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Author Topic: Children Living With Hepatitis C  (Read 8553 times)

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Offline Hep Editors

  • Member
  • Posts: 784
    • Hep Mag
Children Living With Hepatitis C
« on: April 14, 2015, 11:28:56 am »
Did you know that approximately 4000 children in the U.S. contract hepatitis C from their mothers every year? An estimated 6% of infants with HCV-positive mothers will acquire the virus perinatally. This amounts to roughly 23,000 to 46,000 children in the US currently living with HCV.

However, liver disease experts admit that little is known about the pathophysiology of hep C in infants and children. With no mention of the newest HCV treatments, the guidelines for pediatric hepatitis C treatment are outdated.

Generally, HCV progression in children is not as severe or as rapid as it is in adults. Nonetheless, it is still quite serious: There is a 26-fold increased risk of liver-related death associated with chronic HCV acquired in childhood. Cognitive impairment has also been observed in children with HCV. This includes developmental delay, learning disorders, and cognitive deficits.

For more information, click here: http://www.hepmag.com/articles/hepatitis_c_children_2502_26995.shtml

Offline Mike

  • Member
  • Posts: 999
Re: Children Living With Hepatitis C
« Reply #1 on: April 14, 2015, 06:56:45 pm »
I can't think of a sadder thing, than a little kid infected with this pernicious virus!

Thank God for these new medications and the hope that every little kid can be cured, and free from growing up with HCV.

Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline Bituman

  • Member
  • Posts: 157
Re: Children Living With Hepatitis C
« Reply #2 on: April 14, 2015, 09:17:45 pm »

Thank God for these new medications and the hope that every little kid can be cured, and free from growing up with HCV.

Absolutely this.
Age = 59, male, infected likely 1975
DX 07/07 GT 1a
Biopsy 2007:  GR 1, stage 0, HAI = 2/18
Since 2007:  1.48 MM < VL < 11 MM, avg = 5.64 MM
1/26/15, AST=43, ALT=55, VL=3.59 MM
2/5 Start Harvoni 12 weeks; Treat naive
2/20 AST=29, ALT=24, VL=59
3/6 AST=29, ALT=25, VL<15
3/19 AST=24, ALT=22, VL=undet
4/3 AST=29, ALT=25, VL=undet
4/30 EOT, AST=22, ALT=20, VL=undet
5/29 EOT+4, AST=20, ALT=19, VL=undet SVR
7/24 EOT+12, AST=23, ALT=18, VL=undet SVR
10/16 EOT+24, AST=22, ALT=17, VL=undet SVR

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: Children Living With Hepatitis C
« Reply #3 on: April 14, 2015, 11:48:59 pm »
Amen Mike
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!

Offline BubbaT

  • Member
  • Posts: 267
Re: Children Living With Hepatitis C
« Reply #4 on: April 16, 2015, 08:57:57 pm »
Has anyone heard of children or adolescents being treated with Harvoni yet?

Will the insurance deny treatment because of low fibrosis scores?

Age 57 male
Infected late 70's
Diagnosed 95
1a, 2 prev biopsy 95, 2004
Ct 2007, 2015
Treatment Naive
F4 A3. Fibrosure/ CT 2-5-15. Ammonia 222
VL 2.2 mil.
Started Harvoni  3-3-15. 12weeks, finished 5-26-15
4 week VL undetected
12 week EOT undetected


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