1-shot HCV cure on horizon

[spitzbar]

a short interesting read..a novel approach:

http://www.prnewswire.com/news-releases/benitec-biopharma-doses-fifth-patient-and-initiates-additional-trial-site-for-hepatitis-c-trial-300074062.html

[terih]

Oh this is so exciting, I have a Harvoni relapse appointment at the Texas Liver Institute in 2 weeks! Maybe I'll get a chance at this 1 shot dealio! 

[seekir]

Guess there may be good reasons for some of us to be patient and wait a bit longer. I assume they're having some positive results, they seem to be keeping their cards pretty close to their chests.

[spitzbar]

.....it's always a pleasure to see the news was carefully read.   And most certainly explore your opportunity there in Texas, we're sure you'll be considered a valid candidate.   

[pappy]

Very interesting thank you for this information .

[GLCII]

That was deffinitly an interesting read.

[MelHu]

Definitely interesting.  I am genotype 2b and F3 liver status on last 5 days of Sovaldi/RIBA. I was a little down-hearted until now because at my 6 week testing there was still a VL of 49IU/ml and at 8th week 40IU/ml. So I was figuring that I might be a non- responder seeing that most anyone with success has a < VL at 4 weeks.  But this could be an alternate treatment for this silent disease. Probably got it thru blood transfusion at my son's birth in 1979. Just diagnosed in March 2015. Devastating news but so much progress and greatness for those who do achieve SVR. Here's hoping for the best for all on this crazy, scary and happy trip to eradicating this awful disease.
Mel

[beto]

What irony if this works.  I mean how wonderful, but also how very ironic.  When I think of all the lead up to this time.  Folks infected for 20 to 50 years... the transplants... the many years of peg and ribo... the army of liver cirrhotics... the long path of the new drugs to market... and politics to meet the high price.  I never imagined over the decades that a one dose drug might do the trick, but it was one of my three wishes to a gini.

Lovely to know that the battle continues for those in the wings or the ones that have had relapses.  One things for sure, it might drive down the price of Harvoni.

[gnatcatcher]

Earlier this week, I attended a program by four local hepatologists. The one who spoke about what's coming down the pike mentioned a single-shot cure; he estimated it would be publicly available around 2025. He also mentioned treatments arriving in 2016 (a single-tablet therapy for genotypes 1, 4, 5, and 6 that would be safe for those with end-stage kidney disease; also, a possibly better treatment for genotype 3), 2017 (a therapy that would take only 6-8 weeks), and 2018 (one or more treatments that would take only 4 weeks).