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Author Topic: Difficulty Concentrating on Harvoni?  (Read 6736 times)

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Offline Dk0120

  • Newbie
  • Posts: 1
Difficulty Concentrating on Harvoni?
« on: November 11, 2015, 07:39:30 am »
Hi all;

I am on Day 15 of Harvoni Tx.  Genotype 1a - 2 prior treatments with interferon and Ribaviran (18 months) with no results.  Agree that the side effects are nothing like the interferon. I am also waking up at 4:00 am.  Fatigue is certainly a side effect.  Is anyone having difficulty concentrating?  I can't seem to stay on track during the day.  I work from home but stressful job.

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: Difficulty Concentrating on Harvoni?
« Reply #1 on: November 11, 2015, 08:58:22 am »
Dk0120, welcome to the forums. Others have reported difficulty concentrating. I trust at least some of them will find this thread. Best of luck to you.   -Gnatty
« Last Edit: November 11, 2015, 10:08:36 am by gnatcatcher »
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline lporterrn

  • Member
  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: Difficulty Concentrating on Harvoni?
« Reply #2 on: November 11, 2015, 10:01:25 am »
Sleep disruption, on or off hep C treatment will cause concentration problems. Fix that and you may notice improvement. I suggest you talk to your doc.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: Difficulty Concentrating on Harvoni?
« Reply #3 on: November 11, 2015, 12:18:10 pm »
Hi Dk.  It went away, but for my first few weeks (or maybe a month) I was getting those 4am wake-up calls from Harvoni.

And a few others have posted about it too.  Isn't that strange?   :o  What is the magical significance of 4am?!?

Anyway, I was usually able to go back to sleep and, as I said, it finally went away.  It is curious the random similarities I find on the forums.  ???
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline Madelief

  • Member
  • Posts: 60
  • Together we reach the bright site of te road
Re: Difficulty Concentrating on Harvoni?
« Reply #4 on: November 12, 2015, 04:32:24 pm »
Hallo Dk,
I have the same, today is mij day 10 and I must study this week at home for my job. It is blended learning (e-learning) . But I cannot concentrate also like you. Can read the words but they don't land in my brains and just fly away.
I can do things in the household, washing, cleaning up etc but work with needs thinking is difficult.
I have a constant speedy feeling, and sleep is a problem, so I asked my doctor for some sleep medication.
So now I sleep but the speedy feeling and problems with focussing are still there
And I am very introvert these
 days since start Harvoni as if I am living in myself en feel less connected to my husband and daughger, I am not that social als normal.
Wish you all the best and there are coming better days I belief.
Feels a bit like changing my personality these days.

Good luck all!!
« Last Edit: November 12, 2015, 04:35:53 pm by Madelief »
start Harvoni 11-02-2015 (november)
Bloodtest 11-09-2015 alt 45 (before treatment 145)
8 weeks treatment
F1
Bloodworks 11-23-2015
HCV not detectable!!!
Rest of the numers in a normal range : ))))

Offline mauilance

  • Member
  • Posts: 8
Re: Difficulty Concentrating on Harvoni?
« Reply #5 on: November 12, 2015, 10:08:54 pm »
I had the exact same sleep disruption. I thought it was so odd that I would wake up at 3:30 to 4 am every morning and be wide awake. There was no chance of going back to sleep. I tried dosing at different times over the 24 weeks and it made no difference. Taking a nap around 1 in the afternoon seemed to help. Only 90 minutes and then on with the day. I think Harvoini messes with your Circadian rythm. Yes it also confused me. I would have a hard time navigation through town. It gets better, you'll be glad you got rid of the Hep C.
I also was on Interferon/Ribavirin for 72 weeks. Your the first person I've heard of that was put through that Hell with no cure achieved. Best of luck, I've been clear for 4 months now.

 


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