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Author Topic: What to stop on Harvoni treatment  (Read 15740 times)

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Offline hepclady

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  • Posts: 7
What to stop on Harvoni treatment
« on: February 17, 2016, 08:33:15 am »
Hi, New to this list and not sure if this has been covered or how to find it.

I would like to know once you get on Harvoni or other hep c treatment, do you have to stop everything else you are taking?  For example, any herbs at all, vitamins, minerals, bioidentical hormones, etc.

Thank you very much for any information.

Offline Lynn K

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Re: What to stop on Harvoni treatment
« Reply #1 on: February 18, 2016, 02:10:56 am »
Let your doctor know what you are taking is the best answer I can give you. Most of us feel that the less you are taking the better while on treatment so as not to risk interfering with our hard won expensive medicines.

Per the Harvoni prescribing information sheet some herbals are specifically listed as advised against i.e. rifampin & St. John’s wort. There is also very specific instructions for those who take acid reducing meds like Tums, Pepsid or similar Prilosec and similar.

The only thing I took was a multivitamin. If you are taking any prescription medicines please ask your doctor nurse or pharmacist.

Also Harvoni has a nurse line to help with your questions about what is safe to take on treatment.

Here is the link to the prescribing information sheet you should receive this with your prescription:

https://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/harvoni/harvoni_pi.pdf

Here is the contact information for My Support Path for the 24/7 nurse line and access to copay coupons so you may only have to pay $5 per prescription refill

Providers and patients can call 1-855-7-MYPATH (1-855-769-7284) for assistance

http://www.mysupportpath.com/help-along-the-way

« Last Edit: February 19, 2016, 12:06:49 am by Lynn K »
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline lporterrn

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  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: What to stop on Harvoni treatment
« Reply #2 on: February 18, 2016, 02:16:42 pm »
I echo what Lynn said. Even if there is a potential interaction between 2 substances, sometimes it is a matter of adjusting the timing of when you take your medications. In addition to your doctor, talk to your pharmacist. This is a good site to use too (but remember what I said about timing): http://www.hep-druginteractions.org/
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline hepclady

  • Member
  • Posts: 7
Re: What to stop on Harvoni treatment
« Reply #3 on: February 19, 2016, 08:05:12 am »
Hi Lucinda,

Thank you very much for this information.


Offline Forest dweller

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  • Posts: 27
Re: What to stop on Harvoni treatment
« Reply #4 on: March 08, 2016, 09:12:37 am »
Does anyone know about marijuana ??? For help during treatment?

Offline jakas

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  • Posts: 265
Re: What to stop on Harvoni treatment
« Reply #5 on: March 08, 2016, 12:13:02 pm »
u can use it in moderation  4 hours before or 4 hours after the pill, I dont know about the help. I did use it on 2 occasions to sleep as the insomnia was bad
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline coastal girl

  • Member
  • Posts: 36
Re: What to stop on Harvoni treatment
« Reply #6 on: March 08, 2016, 02:20:31 pm »
Hi HepC Lady,  I am a believer in natural medicine.  I did decide to go off the supplements during treatment except B vitamins...I even stopped those 1/2 way thru...nothing was going to mess with me being cured!!! Not that I thought it would.  The nurses and pharmacist at the support line said there was no indicated adverse reactions I still quit them...it was only 3 months.  I never stopped my bio identical hormones!  BTW I am happy to tell you I am undetected per my 12 week post blood test ;D..  Back on my supplements!!!!
8/6/15
1a, shear wave elastography F4
ast-114 alt-80,
viral load 5,941,282

Start Harvoni 9/3/15
ast-131 ast-97, viral load 12,997,415

9/29/15 4 week labs VL 64
ast 34 alt 17
11/25/15  12 wk EOT Undetected!
AST 29 ALT 17  Albumin 3.8 Bil .06

12 week PostTX UNDETECTED!!!
AST 33 ALT 20  Bil. 0.9 Albumin 3.9

25 week Post Tx  UNDETECTED

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: What to stop on Harvoni treatment
« Reply #7 on: March 08, 2016, 06:24:07 pm »
Does anyone know about marijuana ??? For help during treatment?

Help with what during treatment? Are you expecting to have side effects? Most of us here in general had few side effects. Personally I stopped taking anything except the prescribed diuretic I take for edema and my small amount of ascities caused my liver cirrhosis.

Good luck with treatment
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline hepclady

  • Member
  • Posts: 7
Re: What to stop on Harvoni treatment
« Reply #8 on: March 09, 2016, 11:55:54 am »
Can anyone tell me how to reply to individual messages?  I just see a reply button at the bottom of all the messages sent to me.

This is for Coastal Girl. 

Thank you very much for your post.  Good to hear you didn't have to stop bioidentical hormones.  I take a progesterone capsule at bedtime and use a cream during the day.

Great that you were able to stop all other supplements.  I am wondering about magnesium oxide for elimination and some herbal combination that helps with that, too.  I also take an ayurvedic supplement for blood pressure (which isn't terrible, but borderline).  I am planning on stopping those except maybe the magnesium.

I am going to be taking Sovaldi and Daklinza for Genotype 2a/2c.

Thanks for your post.




Offline Lynn K

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  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: What to stop on Harvoni treatment
« Reply #9 on: March 09, 2016, 01:07:07 pm »
Hit the reply button next to the message
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: What to stop on Harvoni treatment
« Reply #10 on: March 09, 2016, 02:12:07 pm »
Can anyone tell me how to reply to individual messages?  I just see a reply button at the bottom of all the messages sent to me.

You can also hit the "Quote" button top right, as I did for this post, Hepclady. And then you type your reply beneath the quoted message - so people an see exactly which posting you are replying to.

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline coastal girl

  • Member
  • Posts: 36
Re: What to stop on Harvoni treatment
« Reply #11 on: March 09, 2016, 02:59:52 pm »
Can anyone tell me how to reply to individual messages?  I just see a reply button at the bottom of all the messages sent to me.

This is for Coastal Girl. 

Thank you very much for your post.  Good to hear you didn't have to stop bioidentical hormones.  I take a progesterone capsule at bedtime and use a cream during the day.

Great that you were able to stop all other supplements.  I am wondering about magnesium oxide for elimination and some herbal combination that helps with that, too.  I also take an ayurvedic supplement for blood pressure (which isn't terrible, but borderline).  I am planning on stopping those except maybe the magnesium.

I am going to be taking Sovaldi and Daklinza for Genotype 2a/2c.

Thanks for your post.

Hello again,
You can lower your blood pressure with food also!  Google flaxseed and BP  and Hibiscus tea and BP and back way off on salt intake.  I recently bought the book How Not To Die by Micheal Greger, M.D.  It's full of whole food dietary benefits!! He's not a supporter of supplements for which I disagree but like all reading materials, take what resonates with your beliefs and needs  :)  My blood pressure raised during treatment on Harvoni, doc said that was not a side effect, I told him that it seems to be the case with quite a few people on treatment.  I hope your treatment goes smoothly with minimal to no side effects and you will be posting undetected soon :D
8/6/15
1a, shear wave elastography F4
ast-114 alt-80,
viral load 5,941,282

Start Harvoni 9/3/15
ast-131 ast-97, viral load 12,997,415

9/29/15 4 week labs VL 64
ast 34 alt 17
11/25/15  12 wk EOT Undetected!
AST 29 ALT 17  Albumin 3.8 Bil .06

12 week PostTX UNDETECTED!!!
AST 33 ALT 20  Bil. 0.9 Albumin 3.9

25 week Post Tx  UNDETECTED

Offline hepclady

  • Member
  • Posts: 7
Re: What to stop on Harvoni treatment
« Reply #12 on: March 10, 2016, 09:27:51 am »
Lynn:

You said to hit the reply button next to the message, but there is not one there.  It only says reply down at the bottom of ALL the messages.  That is what I clicked to send this.


Offline Else

  • Member
  • Posts: 523
  • Appeal, appeal, and appeal again!
Re: What to stop on Harvoni treatment
« Reply #13 on: March 10, 2016, 10:44:25 am »
Lynn:

You said to hit the reply button next to the message, but there is not one there.  It only says reply down at the bottom of ALL the messages.  That is what I clicked to send this.

Hi Hepclady,

When you said "respond to individual messages" are you talking about a private message?

If not, then hit QUOTE button like I did here with your last post.
F/53 yr
diagnosed 1995
Genotype 1a
ALT: 58 AST: 39 ALK: 105
Viral load 4,201,950 IU/ml
Fibroscan 6.5 (F1-F2) Fibrosure 0.36 (F1-F2)
Treatment-naive
After 3 denials, finally approved!
Harvoni 12 wks - start date 9/15/15
4 wk labs 10/14/15
ALT: 12 AST: 16 ALK: 85
HCV Not Detected!!!
8 wk labs 11/10/15
ALT: 13  AST: 15  ALK: 77
12 wk (EOT!) labs 12/8/15
ALT: 11 AST: 15 ALK: 78
HCV Not Detected!!!
10wk posttx labs 2/11/16
ALT: 22 AST: 17 ALK: 61
HCV Not Detected!! SVR10!!!
SVR10 (99.7% Cured!!!)

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: What to stop on Harvoni treatment
« Reply #14 on: March 10, 2016, 01:17:52 pm »
I see you figured out how to reply to my PM aka private message great job!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Wiglaf

  • Member
  • Posts: 14
Re: What to stop on Harvoni treatment
« Reply #15 on: March 14, 2016, 06:44:51 pm »
Does anyone know about marijuana ??? For help during treatment?

I was part of a group of 29 persons receiving treatment for Hepatitis C. Thirteen patients were treated for 8 weeks. I was part of the group that were treated for 12 weeks. We met every two weeks for a Q & A session, and to pick up our meds. Prescriptions varied depending on results of blood work done after each meeting. I took detailed notes at these meetings. A patient in the group asked the doctor/moderator " Is it okay to smoke medical marijuana during treatment?" The doctor reluctantly answered " There is no proof it interferes with treatment."
Contracted: 1969
Treatment: Naïve
Geno 1A
VL: 15,900,000
ALT 38, AST 37
Belirubin 1.3
TX start date: Mar 2, 2015
Harvoni and Ribavirin (1200 mg)
EOT (24 weeks) 5/25/15 undetected
6 mths post TX: undetected 11/24/15
ALT 10, AST 17
Belirubin 0.8

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: What to stop on Harvoni treatment
« Reply #16 on: March 20, 2016, 09:33:18 pm »
Welcome to the forums, Wiglaf. Nice avatar! :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Lynn K

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  • Member
  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: What to stop on Harvoni treatment
« Reply #17 on: March 21, 2016, 01:03:34 am »
One other thought about marijuana is that some are required to be checked for drug use before they can receive treatment and I think while on treatment so if you have to pass a drug test that would be a problem
« Last Edit: March 21, 2016, 01:05:36 am by Lynn K »
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

 


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