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Author Topic: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!  (Read 9645 times)

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Offline Turtle

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  • Posts: 6
Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« on: April 08, 2016, 06:50:10 pm »
So after a number of denials from both Anthem BC and Blue Shield in CA for pretty much all of the Gilead drugs as well as Abbvie, My hepatologist sent me to get a  fibroscan done and based on the results the provider who did the fibroscan invited me into the open label sof/vel 12 weeks vs sof/vel/GS-9857 8 week study. I began treatment 2 days ago on the triple combo/8 week arm. So far I feel fine, the only thing I have noticed is that I have slept better the past 2 nights then I have in quite some time.

Ironically the day I began treatment I got a letter from Blue Shield notifying me that my appeal had been reviewed and that I was approved for Viekira Pak.....

I will post updates of my progress and will add my stats to my sig.
« Last Edit: April 08, 2016, 07:08:51 pm by Turtle »
GT 1b
Likely contracted in 1984
Dx 1990 (declined IF at that time)
Tx naive from 1990-2016
F2-F3 via biopsy in 2009
Fibrocscan 3/7/07 16.6
Sof/Vel/GS-9857 screen visit 3/10/2016 showed VL
of 1,030,000 ALT 74  AST 49
4/6/16 - Randomized to 8 weeks tx Sof/Vel/GS-9857. VL 1,630,000. ALT 63, AST 40.
4/12/16 VL 22. ALT 26, AST 21
4/19/16 VL undetected, ALT 16, ALT 17

Offline KimInTheForest

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  • Posts: 1,972
  • Believe in yourself
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #1 on: April 08, 2016, 08:32:30 pm »
Welcome Turtle! That's great that you found a way to start treatment. Good for you. Keep us posted. :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Philadelphia

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  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #2 on: April 10, 2016, 12:18:49 am »
Looking forward to hearing how you go. Keep us in the loop. :)
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Godisgood

  • Member
  • Posts: 11
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #3 on: April 11, 2016, 01:54:40 am »
Glad all is going well. Looking forward to your progress.

Offline AussieRosa

  • Member
  • Posts: 226
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #4 on: April 11, 2016, 05:21:03 am »
Hi, Turtle. Glad to hear you've started treatment. I hope it goes smoothly and successfully for you. Looking forward to your updates as you go along.
Gt 1a
contracted 1983
Fibroscan 6.1
Treatment naive
VL 2.97M
ALT 38
AST 47
Started Viekira Pak + Ribavirin Tues 19th Jan 2016
Week 4: VL Undetected!
March 5th Ribavirin dose reduction to 800mg from 1000mg
EOT April 11th 2016. VL Not Detected
12 Weeks post EOT: SVR12. Cured with a capital C!!
6 months post EOT: Undetected :-)

Offline Turtle

  • Member
  • Posts: 6
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #5 on: April 25, 2016, 04:16:56 pm »
So I have an update. Been on treatment for 20 days so far. No issues, no side effects at all.

My baseline viral load on 4/6/16 was 1,630,000 copies. ALT 63  AST 40

Week one viral load down to 22 copies. ALT 26  AST  21
Week two ALT  16   AST  17. Will have VL result in a few days.

So at this point, I am thrilled, hopeful, and grateful, and wish success to all others on treatment and/or trying to get treatment (don't give up!).
GT 1b
Likely contracted in 1984
Dx 1990 (declined IF at that time)
Tx naive from 1990-2016
F2-F3 via biopsy in 2009
Fibrocscan 3/7/07 16.6
Sof/Vel/GS-9857 screen visit 3/10/2016 showed VL
of 1,030,000 ALT 74  AST 49
4/6/16 - Randomized to 8 weeks tx Sof/Vel/GS-9857. VL 1,630,000. ALT 63, AST 40.
4/12/16 VL 22. ALT 26, AST 21
4/19/16 VL undetected, ALT 16, ALT 17

Offline HazelAustralia

  • Member
  • Posts: 178
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #6 on: April 26, 2016, 04:20:28 am »
Fab-tastic Turtle!
Female age 53
Australia
Contracted in the 1980's
Genotype 1A
VL 314k

Started treatment with Veikira Pak and Ribaviron on Thursday 17th December 2015
NOT DETECTED, End of Treatment, 16th March 2016

Offline Turtle

  • Member
  • Posts: 6
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #7 on: April 30, 2016, 06:13:16 pm »
Week 2 viral load: Undetected! w00t!

On treatment for 24 days (out of 56) as of today. Continue to have no side effects. Next study visit is week 4 on Tuesday 5/3/16.

The study center I am at is Ruane Medical (http://www.ruanemedical.com/) in Los Angeles (near Olympia Medical Center). If you are looking to get into a study in this area - I would highly recommend them. I used to be a Clinical Research Coordinator myself for 10 years and in my opinion these guys are great and they have a lot of studies - mostly phase 3.
GT 1b
Likely contracted in 1984
Dx 1990 (declined IF at that time)
Tx naive from 1990-2016
F2-F3 via biopsy in 2009
Fibrocscan 3/7/07 16.6
Sof/Vel/GS-9857 screen visit 3/10/2016 showed VL
of 1,030,000 ALT 74  AST 49
4/6/16 - Randomized to 8 weeks tx Sof/Vel/GS-9857. VL 1,630,000. ALT 63, AST 40.
4/12/16 VL 22. ALT 26, AST 21
4/19/16 VL undetected, ALT 16, ALT 17

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #8 on: April 30, 2016, 06:46:06 pm »
Fantastic on both counts, Turtle - undetected AND no side effects!

best,
kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Dormat

  • Newbie
  • Posts: 1
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #9 on: August 28, 2016, 03:35:49 am »
So I have an update. Been on treatment for 20 days so far. No issues, no side effects at all.

My baseline viral load on 4/6/16 was 1,630,000 copies. ALT 63  AST 40

Week one viral load down to 22 copies. ALT 26  AST  21
Week two ALT  16   AST  17. Will have VL result in a few days.

So at this point, I am thrilled, hopeful, and grateful, and wish success to all others on treatment and/or trying to get treatment (don't give up!).

Thanks Turtle for posting your results, it made me feel better after reading your post. I'm trying to get the right treatment so I wont give up.

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Re: Turtle's Solvaldi/Velpatasvir/GS-9857 8 Week DS Adventure!
« Reply #10 on: August 29, 2016, 12:51:50 pm »
Thanks Turtle for posting your results, it made me feel better after reading your post. I'm trying to get the right treatment so I wont give up.

Welcome Dormat! And don't give up! The cure is finally here, and one way or another you will be able to get it. Do you know your genotype and fibrosis stage?

kim :)
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

 


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