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Author Topic: Harvoni and heartburn and other stuff.  (Read 6387 times)

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Offline Yvonne63

  • Member
  • Posts: 5
Harvoni and heartburn and other stuff.
« on: May 15, 2016, 02:21:38 am »
I'm 52 and onto my last 2 weeks of Harvoni (GT 1b) and have been under the impression that I haven't had any side effects until I read a comment in this forum about Harvoni causing heartburn. I have had heartburn, gastric reflux and a few bouts of pancreatitis for years, and just assumed this was normal me. However, the gastric side effects have been bad some days and frightened me into thinking I was still sick, which seems to have been unnecessary. I wonder why this is a side effect?

I had liver cancer last year treated successfully, cirrhosis, hypoglycaemia, platelets 52 and abnormal INR.

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Re: Harvoni and heartburn and other stuff.
« Reply #1 on: May 15, 2016, 09:21:30 am »
I had not seen heart burn as a side effect. I have a hiatial hernia with GERD and made it through 24 weeks of Harvoni but it was a long ride for my heartburn without my Prilosec. My doctor suggested if I could avoid taking Prilosec I should during treatment.

I assume you are following the protocols about acid reducing medicines and Harvoni like Prilosec at the same time as Harvoni on an empty stomach, for meds like Pepcid or Tagamet at the same time and if needed 12 hours after previous dose /before next dose. And for antacids like tums no closer than 4 hours before or 4 hours after taking Harvoni.

Best of luck to you sounds like you have been through the ringer
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!

Offline morab

  • Member
  • Posts: 232
  • Lives in the woods
Re: Harvoni and heartburn and other stuff.
« Reply #2 on: May 15, 2016, 11:52:30 am »
I just took my 28th pill of Harvoni, I have had so much heartburn so it does seem to be a side effect.
Hoping it subsides during second and third month of tx.
You are close to the end of treatment.

3/2016 G 1a
Alt 84
Ast 62
Fibrosis score lab 0.66
quantitation 894,670
4/23/16 day 6, naive Harvoni 12 week treatment
5/27/16 week 4 lab results UNDETECTED AST 23 ALT17

Offline Yvonne63

  • Member
  • Posts: 5
Re: Harvoni and heartburn and other stuff.
« Reply #3 on: May 16, 2016, 08:04:58 am »
Yes Lynn I have been taking antacids (not PPIs) 4 hrs after if desperate. My specialist didn't give me the rundown on antacids, luckily I checked on interactions myself. I will be having a fibroscan next thursday so hoping for some good news. Thankyou to both of u for your responses. It would be nice to be able to say I don't have hep c.

Offline Baxter

  • Member
  • Posts: 87
Re: Harvoni and heartburn and other stuff.
« Reply #4 on: May 17, 2016, 07:25:14 pm »
I've had a lot of problems with occasional heartburn since starting Harvoni, and I drink a lot of carbonated spring water to manage it. Seems to work pretty well.
Gen 1a
Inf. '85
Dx '98
'98 biopsy - Grade 2, Stage 2, VL 7 mil
'01 biopsy - Grade 1, Stage 1, VL 1.5 mil
'08 biopsy - Grade 1, Stage 1, VL 3.5 mil
'12 biopsy - Grade 1, Stage 1, VL 3.5 mil
'16 Fibrosure - Grade I, Stage 3, VL 6.4 mil and 4.8 mil
4/23/16 - ALT 89, AST 50, pltlts 120k. Started 12 wks Harvoni
4/31/16 - ALT 30, AST 21, pltlts 125k
4/14/16 - ALT 25, AST 16, pltlts 126k, VL 69
5/11/16 - ALT 28, AST 21, pltlts 140k,VL <15
9/7/16 - cured. Low Stage 2 fibrosis

Offline Yvonne63

  • Member
  • Posts: 5
Re: Harvoni and heartburn and other stuff.
« Reply #5 on: May 17, 2016, 09:48:42 pm »
Baxter I drink a lot of Pepsi but I doubt it would be as good  for me as carbonated spring water. And I tend to eat more at night while watching tv in bed which wouldn't help :(


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