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Author Topic: New treatment for fibrosis in development  (Read 7133 times)

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Offline HazelAustralia

  • Member
  • Posts: 178
New treatment for fibrosis in development
« on: June 04, 2016, 08:02:05 am »
Have people seen this? What do you think? Apart from the first line, the use of the AAV sounds promising:
https://www.newscientist.com/article/2091961-failing-livers-transformed-into-healthy-organs-by-virus-therapy
Female age 53
Australia
Contracted in the 1980's
Genotype 1A
VL 314k

Started treatment with Veikira Pak and Ribaviron on Thursday 17th December 2015
NOT DETECTED, End of Treatment, 16th March 2016

Offline gnatcatcher

  • Member
  • Posts: 1,372
Re: New treatment for fibrosis in development
« Reply #1 on: June 04, 2016, 08:29:44 am »
The lead scientist is at a reputable institution. I clicked on his name in the link you provided and navigated to his institution's write-up: http://willenbringlab.surgery.ucsf.edu/news--events/ucsf-news.aspx?id=64462
The technique does indeed sound promising. Thanks for posting.
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

Offline FutureThinker

  • Member
  • Posts: 711
  • Onward and upward!
Re: New treatment for fibrosis in development
« Reply #2 on: June 04, 2016, 04:51:07 pm »
Thanks Hazel and Gnatty, I guess this will be the next area we'll be looking into, removing the fibrosis, whenever they figure out how.  Glad to see they are working on it; this is such an amazing time for the field of hepatology!!  FT
Treatment naive
Likely contracted mid-70s
Diagnosed 1a, 2011
F1-2
Harvoni X 12 weeks, completed 5/17/16
Pre-treatment: VL 3 mil, AST 64, ALT 84
4 week labs: VL 30, AST 21, ALT 14
8 week labs: VL UD!!!, AST 22, ALT 16
12 week labs: VL UD, AST 23, ALT 14
2 wk EOT: VL UD
12 wk EOT: VL UD, AST 22, ALT 13 =  SVR 12! Yay! 
Last hep appointment: VL UD, AST 19, ALT 12 = SVR 39! I AM DONE!

 


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