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Author Topic: Starting Epclusa on Tuesday  (Read 119226 times)

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Offline Phoenix17

  • Member
  • Posts: 48
Starting Epclusa on Tuesday
« on: September 11, 2016, 09:00:14 am »
Hello!

I am new to this forum. I found out I had HCV about a month and a half ago. I am GT- 2, and am starting Epculsa on Tuesday Sep 13th. I know there is not a lot of information about Epclusa as it is so new. I am trying to learn as much about it as I can!
I am looking forward to meeting everyone. Going through this with people who understand makes all the difference in the world!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #1 on: September 11, 2016, 12:04:14 pm »
Hello,
   I am right there with you. I will be on day 3 of epclusa today. I also have been trying to find as much info as possible,  however there really isn't any. I have decided to take my pill at night to bypass any possible side effects. Day one was ok for me, I felt an abundance of energy.  Not so much today, my body feels sore and I am feeling mild back pain. My legs are very sore. I am tired but I'm always tired. I have mild discomfort in my liver area. Hoping this is just my body adjusting. I am also very thirsty. Hope everything goes well for You! God bless.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #2 on: September 11, 2016, 01:10:43 pm »
Hi Mw - Glad to meet you! We are in this together. I am going to start this at night as well. From what I have heard from a few others is that your body is adjusting to the meds for sure. After a few weeks it gets a lot better. Drink lots of water too. About a gallon a day will help with the side effects. I have my water ready to go!  Keep me posted on how you are doing. You are on your way to beating this thing!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #3 on: September 11, 2016, 01:22:19 pm »
Nice to meet you as well. This is actually my first post on the forum too. I hope we can help each other through this journey! Keep me updated on how you are feeling please!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #4 on: September 11, 2016, 04:59:45 pm »
I will Mw. You too!

Offline Shannon

  • Member
  • Posts: 17
Re: Starting Epclusa on Tuesday
« Reply #5 on: September 13, 2016, 02:00:28 pm »
I am Shannon, starting Epclusa today, waiting for UPS to deliver it. Just came from my doctor who said I am her first patient to take Epclusa. Hoping for great outcomes for all of us newbies!!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #6 on: September 13, 2016, 03:29:36 pm »
Hi Shannon,
  I hope everything runs smoothly for you! I'm going on day 5. Keep us updated, I think we could all help each other since we are some of the first people prescribed. I'm eager to see how you guys are feeling. I'm having some trouble sleeping which seems to be the root of my problems, but insomnia is nothing new to me. I've been struggling with this for a while. Good luck to you!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #7 on: September 13, 2016, 09:38:45 pm »
Hi Shannon and Mw,

I took my first dose about a hour and a half ago, So far, so good. : )   (7:00pm)

Did you get your Epclusa today Shannon? I hope so! We will kick this!

I will keep you guys posted on how its going. Love to hear how you are feeling

Hopefully you will get some sleep Mw.

Happy Epclusa day!

Offline Shannon

  • Member
  • Posts: 17
Re: Starting Epclusa on Tuesday
« Reply #8 on: September 14, 2016, 01:18:30 pm »
Hi fellow Epclusa friends!! I took my 2nd pill today and so far so good. Pretty sure side effects won't show up the first day or so (if I have side effects at all). For anyone else reading these posts, I went on-line to www.Epclusa.com and they gave me a coupon for $5 co-pay for each prescription!! That is hard to believe as this makes it cheaper than my other prescription meds. Look forward to reporting back in a few days with updates. Hope everyone is feeling great!!

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #9 on: September 14, 2016, 08:24:13 pm »
Glad you are not having any side effects Shannon! I had a few very small headaches today. It was weird! As soon as I felt one coming on, it would go away within about 2-3 seconds. That was it.

I have had swollen ankles for about 4 months. One hurts quite a bit. (Thats why I went to my doc in the first place). I was on my feet a lot today, and the swelling has gone down a lot. From the Epclusa? I guess we will see.

I have the coupon from Gilead as well. The full amount I have to pay for 12 weeks is $15.00. $5.00 a month! Awesome.

Good to see that we are all doing well!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #10 on: September 15, 2016, 07:54:03 am »
Hello,
   Just checking in to update you guys on how I'm feeling. Unfortunately I cannot say I have had no side effects. About an hour after I take this pill, I feel like I've been beaten up. I get pains all over my back, chest, and stomach. The typically subside within an hour. I can sleep for 8 or 9 hours and still wake up feeling extremely drowsy. It's like taking a bunch of Nyquil and going to work. The fatigue lasts all day. I do drink about 4 bottles of water a day. No headaches as of yet. I also do have muscle aches and pains throughout the day, especially in my back and legs. My eyes are so heavy throughout the day and constantly burn. However, I am also still working 10 hour days 6 days a week so maybe my body isn't getting enough rest. I feel worse than I did before starting treatment but I fully expected that and am still immensely grateful to have the opportunity. I'm only 29 and hope to rid myself of this now. I have read that there is a two week adjustment period from other people's experiences. I hope you guys are doing well and getting enough water and rest! Thanks for listening.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #11 on: September 15, 2016, 09:07:43 am »
Hi Shannon! Great to hear you started your Epclusa and will love to hear how it is going! Did you take morning or night? Yes that $5.00 is amazing! Have you been able to navigate this site okay? I am having trouble I am so used to Facebook and nothing like it! I saw some others starting now or soon-I am trying to start soon. How soon do you get blood work or see a Doctor? Keep up your great attitude! Terry
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline Shannon

  • Member
  • Posts: 17
Re: Starting Epclusa on Tuesday
« Reply #12 on: September 15, 2016, 09:22:02 am »
Hi Terry, I am taking med in the morning as I don't want to chance insomnia. I really need my sleep!! I was diagnosed in early July and it took a month to get an appointment with the Hepatologist who then referred me to the Infectious Disease Specialist who did a very specialist blood work up to find out my genotype. That blood test took 3 weeks to get back as it had to be mailed off somewhere. Once doctor prescribed Epclusa it took about another 2 weeks for approval from my insurance as they didn't approve it until doctor wrote them a letter of medical necessity. I started Epclusa on Tuesday, today is day 3. I have blood work and see my doctor every 4 weeks now. Good luck to you and keep us posted. Have a great day!!

Offline Shannon

  • Member
  • Posts: 17
Re: Starting Epclusa on Tuesday
« Reply #13 on: September 15, 2016, 09:23:22 am »
Hey Phoenix, I too am having slight headaches that only last short periods. Today is day 3 so we will see. Wouldn't that be cool if the Epclusa is helping with your leg swelling? Put your feet up my friend.

MW, so sorry you are feeling lousy. I can't imagine not feeling bad at some point as this med is strong enough to cure us!! I too am drinking lots of water. You work too much my friend. I hope this phase passes for you. Take care of yourself and keep us posted.

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #14 on: September 15, 2016, 07:55:02 pm »
Hi My Epclusa fiends!
Mw- Sorry to hear that you are having yucky sides. Are you drinking enough water? I am drinking a gallon a day. It's not as hard as it seems. I have also heard that it takes about 2 weeks for the body to get used to the meds. I hope that it gets better for you sooner. I am tired too. I work 9 hours 5 days a week, have a photography business, work the nursery at church and am a single mom. No wonder we are tired!
Shannon- Glad to hear that it's going well! I take it at night, but not having a hard time sleeping at all. I was pretty amazed at the swelling too!
Momma T- How is it going? Where are you in the process?

Keep the faith everyone!

Offline Shannon

  • Member
  • Posts: 17
Re: Starting Epclusa on Tuesday
« Reply #15 on: September 16, 2016, 08:53:41 am »
Good Morning Everyone!! Checking in to see how you are all doing today. Day 4 and all is well with me. I too am working 9 hour days M-F but my kids are grown and out of the house. Most of my job is at my desk so I try to walk 3 miles a day. Met that goal yesterday but not every day this week. I Hope you all have a restful and uneventful weekend!

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #16 on: September 16, 2016, 06:58:25 pm »
Hi ! Glad to hear you are doing well Shannon. I feel a little more tired today. Not sure if it's just the end of a busy week or the meds. A good nights sleep will help.
Good to see that you are walking. I am always on the go at work and walk a mile during my break. Everything helps, that's for sure.

How is everyone else doing?

Have a great weekend!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #17 on: September 16, 2016, 07:03:08 pm »
Hey Shannon and Phoenix,
    Doing OK over here. Not as foggy today. I also get the slight headaches for 2 to 3 seconds and then it goes away. Keep up the exercise Shannon! Phoenix- it's probably just been a long week. I also took your advice on drinking some more water and feel better. Have a relaxing weekend everyone!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #18 on: September 16, 2016, 07:07:50 pm »
Glad to hear it Mw! Water is your best friend. Have a great weekend!

Offline Shannon

  • Member
  • Posts: 17
Shannon checking on folks
« Reply #19 on: September 22, 2016, 01:49:20 pm »
Hi my friends. Just checking in with everyone on Epclusa. Today is day 10 and I am doing just fine. Anxious to see what my 4 week labs show as my VL was 8,250,000 which is high. Hope everyone is doing well today.

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #20 on: September 22, 2016, 01:59:45 pm »
Hi-I am a week in and just brain fog! Yes-I cannot wait for 4 wk labwork! I just read a gallon so I filled up a container and am going to be more accurate!
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #21 on: September 22, 2016, 02:21:18 pm »
Hey ladies,
    I meant to post on here last night to see how you both were feeling. I am feeling better. Glad to see everyone is in good spirits. I am see my docor in 2 weeks about my 4 week labs. I started with a vL of 55,000. Hoping to see results! I'm sure the brain fog will fade soon, it did for me! Have a good week!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #22 on: September 22, 2016, 02:37:10 pm »
Hi MW!
I am just so glad to hear you are feeling better and happy just be able to see any post from these group of people like you, Shannon, Phoenix and Somewhere in Texas.  I am just little frustrated in using site. I read stay on same thread. Oh how I feel computer challenged! Hope to figure it out! Terry
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #23 on: September 22, 2016, 07:09:12 pm »
Thanks Terry! You will figure it out. If you have email notifications, you can just open your e-mail and anytime someone replies, you'll be notified and will be able to click on the link. That link will bring you right back here to this post. That's how I do it. Best of luck, I am eager to learn about your treatment experience!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #24 on: September 22, 2016, 07:20:38 pm »
Hello friends! Happy to hear from you all. It sounds like everyone is doing well. I am as well. This is day 9 for me and feeling great. Brain fog is still with me, although I walked into a room at work the other day and everything seemed so clear. Kind of like if you get new glaases after 10 years of having the old pair. Not sure if it has anything to do with the Epclusa. I would like to think so. Still a slight headache every once in awhile. Not very often though.

I am excited to get the 4 week labs back too! Take care everyone and keep drinking lot's of water!

Offline Shannon

  • Member
  • Posts: 17
Re: Starting Epclusa on Tuesday
« Reply #25 on: September 28, 2016, 10:09:01 am »
Hello friends, I hope everyone is doing well. I am on day 15 and, for the past couple of days, I am so disoriented, making mistakes at work and putting items where they don't belong. Today I feel like I cannot concentrate at all. Anyone else having this?

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #26 on: September 28, 2016, 01:33:30 pm »
Hey everyone,
     Doing ok over here, ordering my 2nd bottle today. Shannon- I felt this way the first week. I was knocking stuff off counters, forgetting what I was doing. I am a manager and my employees were joking with me about me acting like I was on drugs. It did let up. Are you drinking enough water? Getting enough rest? Take care, hope you feel better.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #27 on: September 28, 2016, 02:30:02 pm »
Hi MW and Shannon
I am so glad to see posts! I have had such brain fog and confusion since starting. I am day 12 and drinking a gallon of water a day.

I just keep hoping everyday when I take my meds that once Hep c is gone-I will become clear headed and not have the pretreatment sleeplessness nights and aches and pains that get me down.

I guess everyone is different! Some people at some point feel great! I am glad no nausea, headache or stomach problems!

Hoping for the best and not giving up! 4 week blood work 10/14! YES
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #28 on: September 28, 2016, 08:48:02 pm »
Hi Everyone! Day 15 and all is well. A few headaches still, but not bad. I still have brain fog, but I have had this for quite a while pre- treatment so nothing has changed in that area. Nothing worse than it was before. Still am tired, but that is nothing new as well! Otherwise feeling pretty good.

Sorry I haven't posted in a while. My dad passed away last week, and it has been a crazy week for my family. I will try to post more often.

I am excited about the 4 week labs as well!

Hope you are feeling better Shannon!

Offline Shannon

  • Member
  • Posts: 17
Re: Starting Epclusa on Tuesday
« Reply #29 on: September 29, 2016, 01:43:33 pm »
Phoenix I am so sorry to hear about your Dad. Bless your heart. Please know my thoughts and prayers are with you and your family.
My second round of pills are coming tomorrow. I am drinking a ton of water. I am still foggy in the brain and get really tired but it could be a lot worse and is only for a short period of time so not complaining. In fact I have been getting some good laughs from my mishaps. Yesterday I did my normal routine, took a shower, packed my lunch, etc. Got to work, opened my lunch and my dirty clothes were in there!! No telling what I packed in my husband's lunch lol. Thinking of you all during our treatment together. Sure is nice to have others to compare side effects with. I cannot wait to hear about everyone's blood test results. Take care of yourselves

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #30 on: September 30, 2016, 12:49:26 am »
Hi everyone of the Epclusa pioneers! You all sound like the Harvoni class of 2015! There was a group of us at the time that were having a lot of trouble getting approved but finally we were all getting our prescriptions & the sharing began. Lots of your sides sound very familiar. Clumsyness, tired some days & then extremely energetic the next, muscle aches etc. But the good news is most likely these will pass & you may not have your current stuff for the duration. I started getting a lot done early in the morning because when I took my pill I was tired for about 2 hours... then back to normal but I do suggest plastic water containers to prevent accidents! A lot of us put our stats in & dates started , 4 wk numbers etc. It would be great since you are literally the first Epclusa patients on this forum. So happy you are all on your way to be HepC free!
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline Philadelphia

  • Global Moderator
  • Member
  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: Starting Epclusa on Tuesday
« Reply #31 on: September 30, 2016, 05:12:03 am »
So sorry to hear of your father's passing Phoenix.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #32 on: September 30, 2016, 07:27:17 am »
Hey everyone,
    Today is day 21 and I'm feeling sluggish and tired. I'm happy to hear from everyone. Phoenix,  sorry about your father. I lost my dad 3 years ago so I understand your pain. Shannon, that is funny! At least you can make light of the situation!  Rosie, thanks for your encouragement and support, I'll keep everyone updated when I get my labs next week. Have a good weekend!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #33 on: September 30, 2016, 08:29:09 am »
Thank you for thinking of me during this time. I appreciate it!

Shannon you made me laugh with your story! I don't have the clumsiness, but the brain fog and fatigue are still there. I had both of those prior to treatment, so its really not too different.

I can't wait to see everyone's 4 week labs!

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #34 on: September 30, 2016, 10:08:45 am »
Pheonix17, so sorry for your loss. You are in my thoughts & prayers.
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #35 on: September 30, 2016, 10:45:55 pm »
Thanks Rosie! It is a difficult time. It will get better as time passes. Kind of like being on treatment.    :)

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #36 on: October 01, 2016, 12:12:07 am »
You are so right.when I found out I had hepc back in 2009 there wasn't a treatment for my genotype yet.I lost my sister,my dad & my father in law all in a month.I was so depressed I thought I was next. I still get weepy thinking about this cure...it seems surreal.
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #37 on: October 03, 2016, 02:17:01 pm »
Hey everyone,
    Just checking in to see how everyone is. I feel increasingly tired and fatigued no matter how much sleep I get. I'm just not feeling well and my job is causing a lot of stress and pressure. I made a mistake at work and am feeling really bad about myself. I'm trying to cope the best way I can but I really have no support besides my fiancee who does not have hep c so he doesn't really understand. Hope everyone is feeling good. Thanks for listening.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline rk

  • Member
  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #38 on: October 03, 2016, 03:03:12 pm »
Please don't beat yourself up. I do not profess to know what you are going through since I will be starting the same treatment this week. However I will be going into it much the same as you. I'll only have one person to talk to on occasion so I am sure it will be lonely. Try to stay strong, the finish line is the goal and your number one objective is to cross that line. Try to cheer up it will get better. I will probably need it myself and hope I am as brave as you and the other veterans. Rod
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #39 on: October 03, 2016, 03:09:11 pm »
Thanks for the support Rod. Wishing you a great and easy treatment!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #40 on: October 03, 2016, 06:45:47 pm »
Hi Friends,
Tomorrow I will be starting week 4 of Epclusa. The time has gone by so fast so far! I am feeling pretty good. Some of my joint pain is gone. I still feel tired, but it's the same as before treatment. The headaches from the first few weeks are gone too.

Next Tuesday I will go in and have my 4 week labs done. Excited and nervous to see what they will be!

MW - Sorry you are not feeling well. Keep on going my friend, you will be glad you did.

Hi rk- Welcome to the forum! To keep the side effects at bay drink lots of water. i drink a gallon a day. It really helps. Keep us posted on how it's going for you.

How is everyone doing?

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #41 on: October 04, 2016, 12:52:00 am »
Hi Mw2324 & Rod, I hope you will find all the support you need right here. I have no idea how I would have gotten through this without the wise people on the forum. I did need more rest at the beginning but as time went on I had a lot of energy & went on mad streaks of productivity. The Hepc was knocked out in the first 3-4 weeks. Think of your body working overtime during that phase. It sounds silly but the time goes by before you realize it you are cured! I wish you could stay home & rest all you want but don't be hard on yourself at work. We are here for you so anytime you feel like no one understands...type away & we will jump in!
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #42 on: October 04, 2016, 01:51:37 am »
Hi Pheonix! Just read your post. Congrats on that first month & upcoming labs. I'm sure you will be even happier when you see results & it's great news. I found that by the end of the first month I was completely used to my routine & drinking water ,resting & trying to be as normal as possible. I just could not tell people at all  so being on here was magic. We were all on the same train... encouraging each other.
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #43 on: October 04, 2016, 09:20:19 am »
Hello fellow Epclusa Aventurers-

Hi Phoenix-I am so sorry to hear of your father's passing. I lost my father right after being diagnosed. I know my father and yours are proud we are fighting this disease.

I am so excited you are in your 4th week!  (make sure lab includes VL, i read some who didn't get it) I am 3 days behind you starting EPCLUSA my 4 wk Labs are 10/14! Is it possible to see a clear that soon???? I have such hopes every day I take a pill.

hi MW-Please take heart and don't beat yourself up. I really think it is the Hep C that makes things hard to rebound from. I have taken to writing notes to compensate for brain fog! I mean like BRUSH your teeth-SHOWER-EAT!

Shannon I loved your story!-I bet you are double checking your lunch, boy are you full of surprises! I know ....Terry, brush your teeth! lol

I really cannot make sense of this year! Well, as I sit here with stitches on my nose (basal cell) feet that are tingling from... What is Tarsal Tunnel Syndrome?? went on vacation and came right back husband hospitalized 2 90% blocked major arteries/ Stents.  Oh and you have Cirrhosis... the good kind!

Well, I am still fighting! I do hope to look back and have a good laugh and be free of Hep C and maybe have a clear thought!

PS I brushed my teeth!

Thank you all for being my support-if it wasn't for this site I think I would Lose it entirely!
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #44 on: October 04, 2016, 05:50:12 pm »
Hey Terry and everyone,
     Hopefully one day we'll all look back on our treatment and laugh at the little things. Hope your husband is feeling better.  Terry -at least you are brushing your teeth! It's awesome that we are all starting this together, all in relatively the same time frame. I know you ladies are looking forward to your 4 week labs and I am eager to hear everyone's outcome. I made my lab appointment for Monday, I start my second bottle Friday. I want to thank you all for being supportive! Thanks everyone.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline rk

  • Member
  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #45 on: October 05, 2016, 12:03:29 am »
Since most Epclusa members post here I have a question that seems related to most treatments. If you take a morning dose do you drink water into the night? If you take a nightly dose do you drink water into the early morning? Do symptoms like being tired, ache, brain fog etc in general last all day; whether you take a morning or evening dose?  I need to decide whats best for me. I am retired & not really pressed to do much of anything day or night. I am up probably up three times a night due to prostate issues. I would like a little more clarity if you will please? I am due to start this Thursday or Friday. Epclusa is being delivered tomorrow 9/5/16

Thanks Rod
« Last Edit: October 05, 2016, 12:07:02 am by rk »
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #46 on: October 05, 2016, 05:34:17 am »
Hi Rod, I already finished my treatment with Harvoni  this year but what I gathered from the forums was that everyone is different & it was all over the map when they would choose to take the meds. For me personally I took @ mid day. I was sharp in the morning & wanted to get all the things done before I got kind of tired or needed to take it easy. You may not get headaches like some of us but the water seems to ease that. Sipping small amounts throughout the day helped me. I was taking large amounts at the beginning & changed that pretty fast. I heard a lot of people taking it at night because they worked & some taking first thing in the morning too. Good luck to you ...rosie
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #47 on: October 05, 2016, 07:04:35 am »
hello everyone!

Thank you Mw-you are so right!-I have to be happy for what I can do! And ease up on myself-especially the forgetfulness. Thank you for asking, my husband is doing good and is back to work. I cannot wait for news of you labwork! Fingers crossed!

Welcome Rosie and Rod!-  I think timing of taking meds all try individually. I can see taking at night and drinking is a good question! Someone here have taken at night. I was most worried my stomach issues history so to wait until 10am. Well after coffee and good breakfast. I didn't want to take any antacids to interfere. As for symptoms mine are Brain fog, I drink from time I get up until I go yo sleep-little throughout day in sips.Keep a gallon Jug on kitchen counter and I like it!

I feel no different and have same chronic pains and health issues I did before treatment -and try to continue to take care of them. I am not sure if it is Epclusa or just stress but I do panic once in a while. That is where this site helps me. Just to know I am not alone. Good luck and I am so happy you will be starting treatment soon! You will figure what works for you! I wish I knew about prostate but sounds like you get up in the night! I fall asleep but get only 4-5 hours even before treatment. Benadryl acts like a charm!

Terry
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline rk

  • Member
  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #48 on: October 05, 2016, 01:32:19 pm »
Thanks Rosie & MomaT, it seems like sipping may be a better way to go. I think I drink a gallon now except quicker and not quite as spread out. I keep 2 gallons in the fridge but most of the day drink filtered tap from a 20 oz glass. I'll start keeping track, thanks again. Rod
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #49 on: October 06, 2016, 08:07:22 pm »
Hello Friends!
Momma T- Thanks for thinking about me. Yes, I do believe our Dads are cheering us on and are going to be right there through everything!
I am getting my 2nd bottle tomorrow, and am going in on Tuesday for the first months labs. Can't wait!
I take my meds at 7:00 at night. I do drink a gallon of water a day. I have 4 separate liter bottles. I drink one before going to work, one at work before lunch, one in the afternoon and one at night. It works for me as I have not had any side effects except a few small headaches in the first few weeks. I don't drink water in the middle of the night, but I do get up to go to the bathroom a few times.   :)
Thanks to everyone here! Your support means the world to me!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #50 on: October 07, 2016, 02:17:29 pm »
Hey everyone,
    Hope you all are well.  I have some moderate brain fog today but pushing through. I start my 2nd bottle today and also saw my doctor and did the 4 week lab tests, now just waiting on the results. My doctor is not too knowledgeable on epclusa, as I am his only patient on it. So thank God for you guys or I wouldn't know what's normal and what's not. And thank God for Google, lol. Have a great weekend!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #51 on: October 11, 2016, 07:20:18 pm »
Hi Friends - Just checking in to see how everyone is doing. I had my 4 week labs today, so we will see soon how everything looks. Starting my 2nd bottle tonight as well.
I hope everyone is doing well!
Mw - What are your lab results? I am sure they are awesome!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #52 on: October 12, 2016, 05:55:48 am »
Hello everyone,
    4 week labs are in...Undetected. ALT and AST decreased to 19 for both. Everything else is normal as well. I'm sure all of your tests will be great also. Keep the hope going.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #53 on: October 12, 2016, 07:38:20 am »
Great news Mw! Glad to hear it.

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #54 on: October 12, 2016, 11:15:57 am »
Thanks Phoenix! You're up next.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline rk

  • Member
  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #55 on: October 12, 2016, 01:56:39 pm »
Mw

I'm glad to hear the great news. You seemed kind of concerned about the melatonin. I was going to tell you my nurse said it was not just me, it interferes with absorption. I did not want to stress so I waited, good for you.

Phoenix, send us more good news
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #56 on: October 12, 2016, 03:20:37 pm »
Rod,
   Thank you for all your information and help. Since last week, I have taken nothing for my insomnia in fear of contradiction. So you really helped me. Thanks again.
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #57 on: October 12, 2016, 05:05:58 pm »
MW! Great UNDETECTED news! look at those liver enzyme numbers too! Most healthy people would love those #19's. You are well on your way. so happy for you!
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #58 on: October 12, 2016, 05:12:28 pm »
Thanks so much for the support Rosie!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #59 on: October 12, 2016, 06:52:29 pm »
Thanks! Had my labs done yesterday, just waiting for results!

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #60 on: October 12, 2016, 11:14:33 pm »
Me, the feeling I get from hearing another person has "slain the dragon" is euphoric ....Even though this is 4 weeks results my Dr. told me the percentage of patients that have your numbers speaks volumes on your positive outcome. These drugs are incredible. I was undetected @ 4 wks. also & I think I kind of settled down & just knew everything was gonna be alright! Phoenix , we can't wait to celebrate with you in a few days!
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #61 on: October 13, 2016, 03:43:15 pm »
Momma T and Shannon, how are you ladies doing? Phoenix, any word on your labs yet?
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #62 on: October 14, 2016, 09:32:17 am »
Hi MW
 I just saw you got a CLEAR at 4 week! YEAH! What labwork script did you get? Mine is just HCV RNA Quantitative PCR. I hope it shows ALT/AST cause mine is crazy high! Thank you for all your encouragement! I really am all over the place emotionally and love the time of day like now-I can feel and think straight-until I take the Epclusa! I will see Dr Thursday and call Gilead today how to adjust time-Just wish I had started at night!  My only reasoning was concern over my stomach upset which I tend to get easily and taking no other meds with the Epclusa. I think they would all be approved so I  may have screwed up cause..... I would rather sleep through this if possible!

Keep up the good vibe-you are so encouraging. We will beat this thing! Oh love the Brain fog is the Good killing Hep C ! Never thought of it that way!
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline Mw2324

  • Member
  • Posts: 138
Re: Starting Epclusa on Tuesday
« Reply #63 on: October 14, 2016, 10:10:52 am »
Hey Momma T,
   The hcv rna quantative pcr is only going to be viral load. For your other tests like liver enzymes, you would need the liver panel done. My doctor ordered 3 tests. But maybe your doctor only wants your viral load right now. Yes, they will better inform you on how to change your time but I know it can be done. The fog will lessen soon. I am still tired sometimes but that's just the medication I suppose. Keep on pushing!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #64 on: October 14, 2016, 12:23:43 pm »
Re: changing your time .....HepC team told me that you can change time by moving about an hour a day till you get to goal time. Hope this helps. I did this & it worked out great.
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #65 on: October 15, 2016, 07:57:58 am »
Hi Rosie!

I take the epclusa at 10am. Thank you for your inputl-so hour to hour is what Gilead said. I wonder what that means. I hope it is hour later each day? Like waiting to 11AM then 12pm 1pm 2pm 3pm 4pm 5pm 6pm 7pm 8pm-that would take (easy 10 days to adjust) Or very hard 9am 8am 7am 6am 5am 4am 3am 2am 1am 12am 11pm 10pm 9pm 8pm-(that takes 2 weeks) Would mean taking it backwards throughout night!
Hope to figure out soon! Just wish I could do it in a day! Have good weekend Rosie!

62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #66 on: October 15, 2016, 10:15:00 am »
Hi Momma T. Yes, you are right . It is a pain if you are making a big change but that's what I did  to change to noon  from early morning. I was waking up so energetic & wanted to use my new found surge to get some stuff done before I went down into the "rabbit hole" for a few hours! I would get pretty dizzy & sluggish for about 2 hours & then slowly get with it again. Also something to remember.... our body is working so hard the first part of your treatment to kill the bad cells that it's no wonder we are exhausted. I did not feel tired the whole time . It gets better! I had a nurse that was working for my specialty pharmacy that counseled me on the time change issue. It would be interesting to ask about  Epclusa too. Have an awesome day EPCLUSA WARRIORS!
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline bluebird

  • Member
  • Posts: 44
  • Life is beautiful! No matter what...
    • https://goo.gl/images/HVZk8m
Re: Starting Epclusa on Tuesday
« Reply #67 on: October 15, 2016, 06:25:50 pm »
I started epclusa yesterday, today is a second day and no any side effects so far...I even wondered to myself if drug is really working... ;D I hope this condition will last to at least half of the 12weeks treatment.  I am taking pills around noon, because first part of day I should be way focused on my job, which  gets easier in the afternoon, and I can leave in case of sickness or dizziness occur. Eating healthy as always( no junk/fast food at all), drinking 2-3 liters a day ( almost a gallon). Staying optimistic, because good mood and positive attitude  will help me to get rid of this monster!
August 2016 before Oct 14/ 4 weeks/  8weeks/ 12week
Genotype 3a.
Viral load 8 million.                <15            N/A    notdet
Comp. cirrhosis
AST        261                          90              70         50
ALT        373                         220             138        89
HCV detected                 <15 detected      NOT DETECT

Offline andrew j

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  • Posts: 476
Re: Starting Epclusa on Tuesday
« Reply #68 on: October 15, 2016, 07:20:08 pm »
Sounds all good, Bluebird.

Offline Mw2324

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Re: Starting Epclusa on Tuesday
« Reply #69 on: October 15, 2016, 07:30:29 pm »
Keep us updated and best wishes Bluebird!
30 yr. old female
Infected in 2006
Genotype 2b
Pretreatment:
F0
Alt 28
Ast 30
Viral load 49,000
Started Epclusa on 9/9/16 -12 week treatment
4 week viral load undetected... ALT 19 AST 19
12 week eot viral load undetected...ALT16 AST 11

Offline Phoenix17

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Re: Starting Epclusa on Tuesday
« Reply #70 on: October 15, 2016, 09:29:13 pm »
Hi Friends - Welcome Bluebird! You have found a great place to be!
I had my 4 wee blood work last week. My VL started at 22006116. At 4 weeks it is down to a mere 36. It's not UD, but it's close! At first I was not happy that it was not a big fat 0. But, it's a huge drop!
Congrats Mw on your UD!!!!
Keep it up everyone, we are doing great!

Offline andrew j

  • Member
  • Posts: 476
Re: Starting Epclusa on Tuesday
« Reply #71 on: October 15, 2016, 09:39:42 pm »
My VL was 18 at 4 weeks, Phoenix (Harvoni) - down from 1.1 million at the start.
(... Must put some stats up!).

I was UND at EOT, and then again at 12 weeks post-treatment (Yay!!!).

... Lots of people still seem to have a bit at 4 weeks.




Offline Phoenix17

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  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #72 on: October 15, 2016, 11:15:04 pm »
Thanks Andrew! It's not a big deal to have a few stragglers, as long as they are gone at the end!

Offline andrew j

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Re: Starting Epclusa on Tuesday
« Reply #73 on: October 15, 2016, 11:59:07 pm »
Indeed.


Offline rk

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  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #74 on: October 16, 2016, 02:10:04 am »
Phoenix & Andrew,  Both of you were down to just a few. It kinda makes me wonder how they were missed. How did they hide and escape sudden death? lol I think they stay holed up, and fight to the end. Its like an inner body WWII. ha ha ha
Obviously I am easily entertained.   
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline Phoenix17

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  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #75 on: October 16, 2016, 09:37:00 am »
I will find them, Rk. Their days are limited! I am the HCV sniper and they will go down!

Offline bluebird

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    • https://goo.gl/images/HVZk8m
Re: Starting Epclusa on Tuesday
« Reply #76 on: October 19, 2016, 09:49:55 pm »
Good evening to everyone!

 It is so exciting ( especially after long day at work) to read positive comments about  your treatment going well. I am happy for everyone who got negative  blood results just 4 weeks after the treatment has been started. It is amazing! It has been almost a week since I started taking epclusa. No any side effects yet. I hope the drug is stronger than a virus, because i feel absolutely no changes... just like i am taking a vitamin pill.  Does anyone else experiencing the same?
 I  am so glad this site exists:)
August 2016 before Oct 14/ 4 weeks/  8weeks/ 12week
Genotype 3a.
Viral load 8 million.                <15            N/A    notdet
Comp. cirrhosis
AST        261                          90              70         50
ALT        373                         220             138        89
HCV detected                 <15 detected      NOT DETECT

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #77 on: October 20, 2016, 12:03:33 am »
Bluebird is kicking ass & taking names! SOOOO HAPPY for you!
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline Phoenix17

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  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #78 on: October 20, 2016, 07:36:25 am »
Hi Bluebird - Congratulations on completing your first week! I am in week 6. There were a few headaches in the first couple of weeks, but feeling good ever since. I have noticed a change in how I feel. For the better for sure! We are taking powerful drugs, so it is working!

Offline bluebird

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  • Life is beautiful! No matter what...
    • https://goo.gl/images/HVZk8m
Re: Starting Epclusa on Tuesday
« Reply #79 on: October 20, 2016, 07:46:27 am »
Hi Phoenix! Good job! I noticed some changes too, like an  elevated energy level. If I felt tired for last couple of months, couple days after I started Epclusa - I feel not being tired after10 hours shift. Honestly, sometimes I force myself to get into a bed to rest( thinking it should be a part of treatment, not to overwork yourself). I think it could be an indication that virus count slowly, but surely drops. Not sure, but I like to think that way! Have a fantastic day, everyone!
« Last Edit: October 20, 2016, 07:57:40 am by bluebird »
August 2016 before Oct 14/ 4 weeks/  8weeks/ 12week
Genotype 3a.
Viral load 8 million.                <15            N/A    notdet
Comp. cirrhosis
AST        261                          90              70         50
ALT        373                         220             138        89
HCV detected                 <15 detected      NOT DETECT

Offline bluebird

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  • Life is beautiful! No matter what...
    • https://goo.gl/images/HVZk8m
Re: Starting Epclusa on Tuesday
« Reply #80 on: October 20, 2016, 07:55:24 am »
Thanks Rosie! Lol! We are going to kick ass and take names together!!!
August 2016 before Oct 14/ 4 weeks/  8weeks/ 12week
Genotype 3a.
Viral load 8 million.                <15            N/A    notdet
Comp. cirrhosis
AST        261                          90              70         50
ALT        373                         220             138        89
HCV detected                 <15 detected      NOT DETECT

Offline KimInTheForest

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  • Believe in yourself
Re: Starting Epclusa on Tuesday
« Reply #81 on: October 20, 2016, 09:49:21 am »
Good luck to all of you on the new drug Epculsa! Wonderful to see this thread.

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline MommaT

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  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #82 on: October 20, 2016, 12:15:22 pm »
Welcome Bluebird!
I am so happy you started Epclusa and have no side effects! That is GREAT!

Hi Kim! Welcome to our group and sure you can give us some great input!

We all started this Epclusa Adventure together with all different experiences! I am so thankful just knowing I have the support from these great people on this forum!

Thank you All!
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline rk

  • Member
  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #83 on: October 20, 2016, 01:07:16 pm »
Hi Bluebird,

I started a week earlier than you. At first I had some brain fog but it is very minimal now if at all. I also had an abundance of energy the first week but it is minimal now as well. Now I feel fairly normal and I hope it continues.
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline bluebird

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  • Life is beautiful! No matter what...
    • https://goo.gl/images/HVZk8m
Re: Starting Epclusa on Tuesday
« Reply #84 on: October 20, 2016, 05:49:52 pm »
I am glad that you are doing fine. Since we have started almost at the same time, we can check our results at the end of the treatment. My dr has never told me that I have to do blood test in the middle of the treatment.  I may call in the couple of weeks and ask her about it.   ;) have a great evening!
« Last Edit: October 20, 2016, 06:23:52 pm by bluebird »
August 2016 before Oct 14/ 4 weeks/  8weeks/ 12week
Genotype 3a.
Viral load 8 million.                <15            N/A    notdet
Comp. cirrhosis
AST        261                          90              70         50
ALT        373                         220             138        89
HCV detected                 <15 detected      NOT DETECT

Offline MommaT

  • Member
  • Posts: 65
  • Tomorrow Is a New Day
Re: Starting Epclusa on Tuesday
« Reply #85 on: October 20, 2016, 08:16:50 pm »
Hello Everyone!
I saw my Dr today and good news is my Viral Load is less than <15! She said Hep c still detected but, that she expected from the Cirrhosis.  She totally went through my file and alleviated alot of my fears of some of my oddly high numbers.

My meld score is a 6. If I get through this I wonder if Compensated Cirrhosis is reversible? I don't drink or smoke and eat really well. Next week I am half way through
and see the light at the end of the tunnel.

Today was a good day! Keep up the good fight! I know it feels like a Roller Coaster!
62 year old Female
Treatment Naive
Genotype 2b
2001 Dx Donated blood after 9/11
2002 Biopsy F1
2016 Fibroscan 15 F4
Comp Cirrhosis Stage 1
pretreatment VL 1,722.660 mil
platelets 122 low
alpha 2 Macroglobulins 647
Apolipoprotein A-1 214
GGT 67 high
AFP Serum Tumor Marker 11.4
ALT 563 AST 332
2016 Sept 16 Epclusa started
4 wk VL <15 HCV Detecte
ALT 19 AST 18
8 wk VL HCV Undetected!
12/8/16 EOT Yipee!
12 wk VL HCV Undetected
SVR 12
SVR  24  10/5/2018 HCV Undetected   12/10/18 DETECTED????????

Offline elias

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  • Posts: 285
Re: Starting Epclusa on Tuesday
« Reply #86 on: October 20, 2016, 09:28:23 pm »
Hi MommaT

I've read a scientific report showing compensated cirrhosis was reversed in a significant number of those who cleared the virus. Not as high a percentage as those regressing from F2-->F1 for example. But seemed significant percentage. It does take some time from after the virus is cleared. Which in your case is obviously headed there

I hope I could find the report. I'll link to it if I do

Unfortunately, reports of fibrosis/cirrhosis regression do not give lifestyle factors which influence the success of regression. But I'm sure hoping its more than just a matter of genetics or luck. I too am very interested in such regression, because I'm F3

I'm also hoping that with so many more clearing this virus than ever before, there'll be intensive interest n research on fibrosis/cirhosis regression.

I'm waiting  a few more days before starting the Epclusa, because I'm having a bout of  horrific insomnia, and waiting for that to settle some before embarking on that journey. Will definitely keep you posted.

-elias
« Last Edit: October 20, 2016, 09:30:00 pm by elias »
Contracted HCV ~age 12
Diagnosed: September 2016 GT2b
F3 by Fibrosure: 0.66
Necroinflammat activity: A3 0.76
================
VL Sep. 12, 2016: 1.44 million/ Log: 6.157
AST:71/ ALT:114   Sept. 1, 2016 Before treatment
==================
4 week after beginning  Epclusa:
Viral Load: UNDETECTED
AST 17/ALT 11
===============
Began Epclusa:  October 22, 2016
End of Treatment [EOT]: January 13. 2017
====================
EOT+4 Weeks: UNDETECTED
====================
SVR 12 April14-HCV Not Detected

Offline bluebird

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  • Life is beautiful! No matter what...
    • https://goo.gl/images/HVZk8m
Re: Starting Epclusa on Tuesday
« Reply #87 on: October 20, 2016, 09:36:27 pm »
Congratulations, MommaT! Baby steps.. Slowly, but surely you are getting there. Don't loose the hope. I have the same expectations from treatment too and same hope!!!!!!
August 2016 before Oct 14/ 4 weeks/  8weeks/ 12week
Genotype 3a.
Viral load 8 million.                <15            N/A    notdet
Comp. cirrhosis
AST        261                          90              70         50
ALT        373                         220             138        89
HCV detected                 <15 detected      NOT DETECT

Offline elias

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  • Posts: 285
Re: Starting Epclusa on Tuesday
« Reply #88 on: October 20, 2016, 09:41:50 pm »
Hi again, Epclusa Family:

To: MommaT:

In the meantime , heres one link of cirrhosis regression. Though its not the one I had in mind which gives more statistical detail and charts..The one i had in mind was a presentation at a recent Liver Conference.

There's another such conference coming up -I think in Boston-early this November. So hopefully, more on all this will come forth

But for meanwhile:

http://www.medscape.com/viewarticle/839337_3

Congrats on your four week victory
« Last Edit: October 20, 2016, 09:48:39 pm by elias »
Contracted HCV ~age 12
Diagnosed: September 2016 GT2b
F3 by Fibrosure: 0.66
Necroinflammat activity: A3 0.76
================
VL Sep. 12, 2016: 1.44 million/ Log: 6.157
AST:71/ ALT:114   Sept. 1, 2016 Before treatment
==================
4 week after beginning  Epclusa:
Viral Load: UNDETECTED
AST 17/ALT 11
===============
Began Epclusa:  October 22, 2016
End of Treatment [EOT]: January 13. 2017
====================
EOT+4 Weeks: UNDETECTED
====================
SVR 12 April14-HCV Not Detected

Offline elias

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  • Posts: 285
Re: Starting Epclusa on Tuesday
« Reply #89 on: October 20, 2016, 10:32:10 pm »
Anna Maria Crissien's report at AASLD Conference 2015 :

http://www.hcplive.com/conference-coverage/aasld-2015/qa-with-ana-maria-crissien-from-scripps-green-hospital-studying-regression-in-liver-disease

Worth looking at the actual report if youre stickler for details. Cant find it yet
Contracted HCV ~age 12
Diagnosed: September 2016 GT2b
F3 by Fibrosure: 0.66
Necroinflammat activity: A3 0.76
================
VL Sep. 12, 2016: 1.44 million/ Log: 6.157
AST:71/ ALT:114   Sept. 1, 2016 Before treatment
==================
4 week after beginning  Epclusa:
Viral Load: UNDETECTED
AST 17/ALT 11
===============
Began Epclusa:  October 22, 2016
End of Treatment [EOT]: January 13. 2017
====================
EOT+4 Weeks: UNDETECTED
====================
SVR 12 April14-HCV Not Detected

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #90 on: October 20, 2016, 10:39:01 pm »
Awesome Momma T! Great news indeed. We both have a few pesky ones to get rid of. I started with a VL of 22 million and after 4 weeks its down to a mere 36. I am sure in the next few days it will be long gone for both of us if it's not already!

You are right about feeling like a roller coaster!

Offline Rosie13

  • Member
  • Posts: 297
Re: Starting Epclusa on Tuesday
« Reply #91 on: October 21, 2016, 04:45:51 pm »
Hey Momma T! I know there are some very wise people on here that know about cirrhosis . I had a fibro score of F3 & was told that it would take quite some time to heal & have a better score. But on my 24 week final appointment @ Mayo Clinic they were celebrating my score which went to F1! You sound like you have all your lifestyle choices perfect so don't be surprised to get a better c # too. Asong as you feel good those numbers are just that ...
Labs August 15,2015
Genotype 1b
AST 112 U/L
ALT 181 U/L
HCV 192,000 IU/mL
Fibroscan F2-3
Started Harvoni Sept. 5, 2015
4wk. labs Oct. 2,2015
AST 21 U/L
ALT 27 U/L
HCV UNDETECTED!!
8wk. labs Nov.5,2015
AST 16 U/L
ALT 19 U/L
HCV UNDETECTED!!
12 wks.post tx.feb.11,2016
UNDETECTED!!!
24 wks. post tx. may 16,2016
UNDETECTED Fibroscan  F-0!!!!!

Offline rk

  • Member
  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #92 on: October 21, 2016, 11:17:48 pm »
bluebird,

Sure we can compare results but at the end we should both be undetected! You can enter your labs in the sig file at the end of your profile. I imagine your doctor will order at least 1 lab before end of treatment just to make sure all is well. I get my first lab results next Tuesday. My vl was low to start. Do you know your results from when you started? If you do not know ask, it should be available.
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline elias

  • Member
  • Posts: 285
Re: Starting Epclusa on Tuesday
« Reply #93 on: October 22, 2016, 10:14:48 pm »
Hi:

I just took my first Epclusa!!

Proud to be joining this little Epclusa family here. And thank you Phoenix for starting this thread.

I spoke to my GI and he said that once virus is cleared, many regress a few levels on the fibrosis scale.  Some even back to normal. Because the liver is the most self-regenerating organ. Intuitively , I feel there are concrete things we might do to improve those odds of healing. So hope to learn more about this. Thank you Rosie for confirming this liver "self-regenerating" concept a few days ago.

My GI scripted me some low-dose diazepam , since I fear anxiety and insomnia the most. but this group will help me more than the benzo. Hope I wont need it.

It's been an incredible journey so far. This little group is kinda making history, because we're "first generation" to be taking this wonderful medicine.

I'm hopeful, though a tad nervous. Happy to be joining you all

Will keep you posted

~elias
« Last Edit: October 22, 2016, 11:22:35 pm by elias »
Contracted HCV ~age 12
Diagnosed: September 2016 GT2b
F3 by Fibrosure: 0.66
Necroinflammat activity: A3 0.76
================
VL Sep. 12, 2016: 1.44 million/ Log: 6.157
AST:71/ ALT:114   Sept. 1, 2016 Before treatment
==================
4 week after beginning  Epclusa:
Viral Load: UNDETECTED
AST 17/ALT 11
===============
Began Epclusa:  October 22, 2016
End of Treatment [EOT]: January 13. 2017
====================
EOT+4 Weeks: UNDETECTED
====================
SVR 12 April14-HCV Not Detected

Offline rk

  • Member
  • Posts: 99
Re: Starting Epclusa on Tuesday
« Reply #94 on: October 22, 2016, 11:02:47 pm »
Hi Elias, welcome to the family. My doc said the liver heals but never mentioned by how much. I imagine that is individual. Were similar with anxiety & insomnia. I mellowed out after I started. My regular doc gives me a script for diazepam but my Hepatologist said try to avoid.

I am on my third week. When I started my brain felt buzzed about an hour after a dose. It was really brain fog setting in. Then after 10 days or so I do not notice anything after a dose. My thought process seems fairly normal. I suppose we are pioneers to epclusa however the ones before us are the real pioneers. I'll give them a nod, I would not have wanted to be in their shoes. Best wishes to you and everyone.   
9/14/2016 pre-treatment
GT 2
Viral load 2940
Platelets 142
AST        16
ALT        6
Fibrosis stage  F3
LSM        10.1 kPa
Started Epclusa 10/7/16
EOT + 12 weeks HCV undetected

Offline bluebird

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    • https://goo.gl/images/HVZk8m
Re: Starting Epclusa on Tuesday
« Reply #95 on: October 22, 2016, 11:31:17 pm »
@rk- added my numbers...
August 2016 before Oct 14/ 4 weeks/  8weeks/ 12week
Genotype 3a.
Viral load 8 million.                <15            N/A    notdet
Comp. cirrhosis
AST        261                          90              70         50
ALT        373                         220             138        89
HCV detected                 <15 detected      NOT DETECT

Offline Phoenix17

  • Member
  • Posts: 48
Re: Starting Epclusa on Tuesday
« Reply #96 on: October 23, 2016, 09:18:51 am »
Congratulations Elias on your first dose!! I know it feels so good to start treatment. You are well on your way! Keep us posted on how you are doing.

Offline sammantha55

  • Member
  • Posts: 20
  • geno 2b dx in 2006
Re: Starting Epclusa on Tuesday
« Reply #97 on: October 23, 2016, 03:18:14 pm »
Elias, congrats on starting your first dose, keep us posted on how you're doing, I'm right behind you in about a week .

Offline andrew j

  • Member
  • Posts: 476
Re: Starting Epclusa on Tuesday
« Reply #98 on: October 23, 2016, 05:03:49 pm »
Hi Elias,

I only noticed on Thursday that you had been approved for Epclusa!
These threads can be weird like that, can't they?

... Of course, I was over the moon!

I am so pleased that 'the system' worked for you as it should, and hope (of course) that you have a smooth and uneventful ride through treatment.

Best wishes,
A.

Offline elias

  • Member
  • Posts: 285
Re: Starting Epclusa on Tuesday
« Reply #99 on: October 23, 2016, 08:30:09 pm »
Thank you , Phoenix, Samantha, Andrew

I did have some symptoms last night a few hours after I had taken my first Epclusa.

They werent anything new, just more intense forms of things already bothering me prior to all this. Things like hyperaccusis, meaning sounds seem louder than they actually are.  Same with visual stuff..I'm in general prone to it. Hard to say yet if these minor things are placebo/nocebo effects. There are also some positive effects. I slept really well last night and many hours. Feel more energy today than in long time.. Someone noted I seem much better. Still too early to tell.

Andrew said:

Quote
I am so pleased that 'the system' worked for you as it should, and hope (of course) that you have a smooth and uneventful ride through treatment.

The system did work. But probably because for years the HCV advocacy movement had taken on the  insurance companies and were prevailing in the courts. So kudos to all who laid that foundation.

I'm using this little biofeedback gadget-Resperate- which slows down your breathing to help with insomnia. Its a bit overpriced, because its marketed to lower blood pressure. But can be used for other issues. Too early to tell if its helping  me with the psychological type symptoms.

Will keep you posted
« Last Edit: October 23, 2016, 08:32:46 pm by elias »
Contracted HCV ~age 12
Diagnosed: September 2016 GT2b
F3 by Fibrosure: 0.66
Necroinflammat activity: A3 0.76
================
VL Sep. 12, 2016: 1.44 million/ Log: 6.157
AST:71/ ALT:114   Sept. 1, 2016 Before treatment
==================
4 week after beginning  Epclusa:
Viral Load: UNDETECTED
AST 17/ALT 11
===============
Began Epclusa:  October 22, 2016
End of Treatment [EOT]: January 13. 2017
====================
EOT+4 Weeks: UNDETECTED
====================
SVR 12 April14-HCV Not Detected

 


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