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Author Topic: second attempt atbtreatment  (Read 5181 times)

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Offline hguy

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  • Posts: 6
second attempt atbtreatment
« on: December 06, 2016, 09:43:08 pm »
Hi all. Im new here. Im 49 and this is my second attempt at treatment. Just got my 4 week labs on Harvoni and viral load has gone from 1.4 million to 36. Im encouraged but tring not too get too excited. I previously was treated with ribavarin, victrellous and interferon for 11 months. My viral load went away then durring treatment only to return. Genome type 1a. Wondering how other people with same genome type have responded to Harvoni at both the 4 week labs and 12 week post.

Offline Philadelphia

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  • Posts: 1,157
  • It only looks like I know what I'm doing
Re: second attempt atbtreatment
« Reply #1 on: December 07, 2016, 02:47:15 am »
Not harvoni but 1a and took viekira Pak. Has a vl of 45 at 4 weeks. Now,  14 months post treatment I am still undetected. And happy.  Very happy.
CURED SVR24  Class of 2015
Wk 12 post EOT 30.11.15: ALT 14 AST 22 GGT 22 VL UND
Week 19 07.08.15: ALT 17 AST 23 GGT 25
Week 12 18.06.15: ALT 21 AST 23 GGT 28
Week 8 25.05.15: ALT 23 AST 27 GGT 30 VL UND
Week 4 20.04.14: ALT 30 AST 36 VL 40
Treatment start 23.03.15: ALT 137 AST 185 VL 342,600
Cirrhosis Child-Pugh A, Genotype 1a - Viekira Pak + riba 24 weeks
Total failure interferon/ribavirin/boceprovir Mar 2013
https://www.hepmag.com/blogger/grace-campbell

Offline Lynn K

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  • Posts: 4,544
  • Get tested, get treated, get cured, fight Hep c!
Re: second attempt atbtreatment
« Reply #2 on: December 07, 2016, 03:36:47 am »
I am also Genotype 1A. I was diagnosed back in 1990. I treated with interferon mono therapy 3 shots of week of just interferon. Then they discovered ribavirin treated with the new pegalated interferon (pegintron) just one shot a week and the riba pills. I was a null responder my viral load didn't change at all on treatment.

I got in a clinical trial and was taking interferon ribavirin and a trial med. I don't remember what it was but is was not incivek (telaprevir) again a null responder.

By the time incivek was approved I has cirrhosis and they would not let me treat because the odds of it working were very low and as I had cirrhosis it could be very dangerous for me.

I also treated with Sovaldi & Olysio about 6 months before Harvoni was approved. I was not detected on treatment but after treatment ended 12 weeks post I was found to have relapsed. That was September 2014

In Nov 2014 I started taking Harvoni for 24 weeks. I later asked my doctor about adding ribavirin because of my past history and having liver cirrhosis. She agreed so I took ribavirin for 15 of those 24 weeks.

I was not detected at 12 weeks, 24 weeks and 44 weeks post treatment and am now cured. I am not the only one with a similar history who was cured by Harvoni.

You will be too

Best of luck on treatment :)
Lynn
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline hguy

  • Member
  • Posts: 6
Re: second attempt atbtreatment
« Reply #3 on: December 08, 2016, 07:27:18 am »
 Congrats on the success of your treatment. Thank you for the reply and encouragement. My next labs are at end of December. I w :)ill share my results. :)

Offline gnatcatcher

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  • Posts: 1,372
Re: second attempt atbtreatment
« Reply #4 on: December 08, 2016, 09:11:49 am »
hguy, wishing you a VERY happy, hep-free new year! Glad to see you're already helping someone else on these forums.

Gnatty
9/29/71 transfusions
HCV genotype 1a
7/09/15-9/30/15 Harvoni

Before treatment:
Viral Load 9,490,582
FibroScan 19.5 kPa [F4]
ALT 262
AST 217
ALP 183

Most recent:
VL still UNDETECTED (SVR 102)
FibroScan 7.6 kPa [F1-2]
ALT 15
AST 20
ALP 85

 


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