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Author Topic: Please help me interpret test results  (Read 7391 times)

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Offline ItsMe914

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Please help me interpret test results
« on: June 03, 2017, 01:58:57 pm »
Hello all, I just got back the results of some recent blood work, due to feeling lethargic and "icky", and I'm wondering if you can help me in figuring out what they mean. My doctor is closed for the weekend and I'm freaking out a bit.

Hepatitis B Core Antibody, Total Nonreactive - Nonreactive     
Hepatitis B Surface Antigen Confirmation - Nonreactive

Hepatitis B Surface Antibody
Hepatitis B Surface Antibody Result - <3.10
Hepatitis B Surface Antibody Interpretation - Nonreactive

Hepatitis B Surface Antigen w/Rflx Confirmation
Hepatitis B Surface Ag Index - 1.33  H
Hepatitis B Surface Antigen - Reactive

I'm wondering how I can be non reactive for 'Surface Antigen Confirmation', but reactive for 'Surface Antigen w/Rflx Confirmation'. Does this mean anything? Do I have HBV? 

Thank you in advance!

Offline ItsMe914

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  • Posts: 8
Re: Please help me interpret test results
« Reply #1 on: June 03, 2017, 04:08:13 pm »
I'm not sure if it will help, but here are these numbers as well.  Thanks again for any insight you can offer!

GFR Estimated (NonĀ­African American) 95
GFR Estimated (African American) 111
BUN/Creatinine Ratio 12.9
Sodium 143
Potassium 4.0
Chloride 104
Carbon Dioxide (CO2) 26
Anion Gap 14
Protein, Total 7.3
Albumin 4.6
Globulin 2.7
Albumin/Globulin Ratio 1.7
Calcium 9.9
Alkaline Phosphatase 41
Alanine Aminotransferase 29
Aspartate Aminotransferase 24
Bilirubin, Total 0.7

Offline Lynn K

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  • Get tested, get treated, get cured, fight Hep c!
Re: Please help me interpret test results
« Reply #2 on: June 04, 2017, 01:12:00 am »
What has your doctor who ordered these tests said?

Have you had any liver enzyme tests done? Would be ALT and AST as part of a hepatic function panel or a comprehensive metabolic panel.
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline ItsMe914

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  • Posts: 8
Re: Please help me interpret test results
« Reply #3 on: June 04, 2017, 11:07:28 am »
What has your doctor who ordered these tests said?

Have you had any liver enzyme tests done? Would be ALT and AST as part of a hepatic function panel or a comprehensive metabolic panel.

Nothing yet.  They're closed for the weekend, so I was trying to get some information to calm my mind in the meantime.  I believe some of the urinalysis figures above are liver enzymes, but this is all new to me so I'm, not sure. 

The burning question is how I could be reactive for the surface antigen test but then nonreactive to what they're calling surface antigen confirmation. 

Offline Lynn K

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Re: Please help me interpret test results
« Reply #4 on: June 04, 2017, 06:24:18 pm »
As far as the test yeah after google it looks like a complete metabolic panel it is a blood test

Alanine Aminotransferase is (ALT) would you know the reference range your lab uses my lab uses 0 to 32 so that makes your 29 normal range assuming your lab uses the same numbers.

Aspartate Aminotransferase is AST my lab uses 0 to 40 for the reference range so again your 24 is normal range per the scale my lab uses.

As far as the hep b testing not my area of knowledge the majority here are patients most who had hep c just a few with hep b.

Primarily this is an online support group. We cannot diagnose any medical condition. Lucinda is a medical professional. I did send her a message so hopefully she will chime in soon and answer about the hep b test results
« Last Edit: June 04, 2017, 06:27:24 pm by Lynn K »
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline ItsMe914

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Re: Please help me interpret test results
« Reply #5 on: June 04, 2017, 07:29:31 pm »
Got it, thanks Lynn!  I was hoping someone else had similar seemingly contradictory results that could shed a little light for me.  Better believe I'll be calling the doc first thing tomorrow!

Offline lporterrn

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    • LucindaPorterRN
Re: Please help me interpret test results
« Reply #6 on: June 05, 2017, 03:02:21 pm »
Hi,
I hope you have had a chance to talk to your doc by now. I have an educated guess as to what this all means, but like you, I am baffled by the non reactivity for 'Surface Antigen Confirmation', but reactivity for 'Surface Antigen w/Rflx Confirmation'.

So, as much as I'd like to help, you don't need guesses. Please let us know what the doc says.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline ItsMe914

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  • Posts: 8
Re: Please help me interpret test results
« Reply #7 on: June 05, 2017, 05:30:08 pm »
Thanks, Lucinda!  At this point, I'll take an educated guess.  I haven't been able to speak to me doctor and have left two voicemails.

Offline ItsMe914

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  • Posts: 8
Re: Please help me interpret test results
« Reply #8 on: June 05, 2017, 05:34:50 pm »
Here is the actual result:



Offline lporterrn

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  • LucindaPorterRN
    • LucindaPorterRN
Re: Please help me interpret test results
« Reply #9 on: June 06, 2017, 06:55:46 pm »
My guesses (and I mean guesses), are that either one of the tests is wrong (the reactive test is only weakly reactive) or that you were recently exposed and your immune system is fighting this infection. The fact that your liver enzymes are normal is heavily in your favor.

Please let me know what your doc says.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline ItsMe914

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  • Posts: 8
Re: Please help me interpret test results
« Reply #10 on: June 06, 2017, 07:06:06 pm »
I finally spoke to my doctor.  She believes that the reactive surface antigen test then prompted the confirmatory test, which came back as nonreactive, meaning I am negative.  She didn't give me an overwhelming sense of confidence though.  She said she will get a second opinion and call me if anything is of concern before my next appointment.  I'm still not sure how I could test as reactive if I don't have it, but I hope she's right. 

Offline lporterrn

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Re: Please help me interpret test results
« Reply #11 on: June 06, 2017, 08:45:32 pm »
You were weakly reactive. I suspect you were exposed but not infected. I would retest in 6 mos. And get a hep B vaccine.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline ItsMe914

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  • Posts: 8
Re: Please help me interpret test results
« Reply #12 on: June 16, 2017, 03:18:20 pm »
I finally had the chance to meet with my doctor today.  Her interpretation since I was reactive for Hep A antibodies, is that I was immunized for both A and B at one point and my Hep B antibodies are no longer strong enough that they registered as weakly reactive antigens.  It seems far-fetched.  Nonetheless, she assured me that the confirmatory test is the final say and since that showed as nonreactive that I negative.  She also said since I don't work in the healthcare field, nor am I traveling to any high-risk countries, that I don't need to get retested. 
« Last Edit: June 16, 2017, 10:09:10 pm by ItsMe914 »

Offline lporterrn

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  • LucindaPorterRN
    • LucindaPorterRN
Re: Please help me interpret test results
« Reply #13 on: June 16, 2017, 08:52:20 pm »
Reasonable explanation, but if you don't have certainty that you were immunized for hep A and B then it is also possible you had hep A earlier in your life and never had hep B. Perhaps talk to her about getting the hep B vaccine.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

 


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