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Author Topic: A Single Molecule May Drive Difference in Hep C Infection in Humans vs. Chimps  (Read 3609 times)

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Offline Hep Editors

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    • Hep Mag
Searching for reasons why hepatitis C virus (HCV) is so insidious in humans but typically innocuous in chimpanzees, researchers identified a single molecule that is more protective against the virus in chimp livers compared with all but a very few number of humans.

Publishing their findings in PLOS Pathogens, researchers studied interferon molecules. Interferon is a type of immune-system alarm bell that, in a liver infected with HCV, signals the liver cells to produce antiviral molecules. A particular type of interferon known as IFNλ4is associated with a lower chance of clearing HCV spontaneously without treatment.

For more...
https://www.hepmag.com/article/single-molecule-may-drive-difference-hep-c-infection-humans-vs-chimps

 


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