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Author Topic: Upcoming International Liver Congress in Vienna/  (Read 11322 times)

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Offline MEG

  • Member
  • Posts: 304
Upcoming International Liver Congress in Vienna/
« on: April 08, 2015, 05:09:31 pm »
April 22-26. Hopefully, we'll get some updates....Lucinda, will you be attending?

http://www.easl.eu/_events/the-international-liver-congress/the-international-liver-congress-2015-50th-annual-meeting-of-the-european-association-for-the-study-of-the-liver

Hopefully we'll get some initial real-world data on Harvoni and the other treatments.

Looks like Abbie has some promising results....for starters...although looks like it's just a teaser---they will not be disclosing full results until later this year.

"""""Preliminary results from a Phase 2b trial (n=79) evaluating ABT-493 and ABT-530 in non-cirrhotic HCV-1 patients show a sustained virologic response at four weeks post treatment (SVR4) of 99% (n=78/79). The results include GT1a and GT1b, treatment-naive and pegylated-interferon and RBV prior null responders. Data from this study will not be presented at ILC but will be released at future medical meetings."""""
Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.

Offline iana5252

  • Administrator
  • Member
  • Posts: 187
Re: Upcoming International Liver Congress in Vienna
« Reply #1 on: April 08, 2015, 06:13:24 pm »
Hep will be covering the conference. We will post a link when the conference coverage has started. For past coverage, check out this link.

http://www.hepmag.com/conference_coverage.shtml

Offline charly8

  • Member
  • Posts: 113
Re: Upcoming International Liver Congress in Vienna/
« Reply #2 on: April 10, 2015, 09:44:40 am »
1a, VL  1.05 Mil, ALT 47
Fibrosure F3 December 2014
Fibroscan F0-F1 March 2015
1995 INT & RYB -non-responder
2007 PEGIN & RYB 72 weeks tx - partial responder relapsed
1/23/15 Started Harvoni 12 weeks, EOT 4/17
2 week blood work -  <15 Und. (ALT 25)
4 week blood work - <15 Und. (ALT 29)
2/20/15 added RYB (4 weeks into 12 of tx)
8 week blood work - <15 Und. (ALT 23)
(EOT) 12 week blood work - <15 Und.
4wk POST tx VL - Und. (ALT16, AST 17)

Offline MEG

  • Member
  • Posts: 304
Re: Upcoming International Liver Congress in Vienna/
« Reply #3 on: April 11, 2015, 03:54:50 pm »
Thanks for that post, Charly. Interesting results.

As I'm sure you know, the investors over there are on top of all these companies.  Can recite trial data in their sleep. Great resource.

Scanning those abstracts---I truly think that 12 weeks Harvoni will be standard in the not too distant future...the risks of under-treating/relapse don't bare the benefit of the initial lower $$$ and human cost. Imo. Although we have Paul here who thank God is negative post 8 weeks. I'm still glad my doc and I  eventually pushed for and got the 12 weeks regimen--8 weeks was the initial authorization.
« Last Edit: April 11, 2015, 06:11:12 pm by MEG »
Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.

Offline MEG

  • Member
  • Posts: 304
Re: Upcoming International Liver Congress in Vienna/
« Reply #4 on: April 11, 2015, 04:10:29 pm »
Charly, just noticed your EOT is April 17...Mine April 21....Wooooooooo!
Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.

Offline charly8

  • Member
  • Posts: 113
Re: Upcoming International Liver Congress in Vienna/
« Reply #5 on: April 11, 2015, 05:16:26 pm »
I agree Meg about the 12 weeks.

About the end of treatment for us, it seems that time is now moving so slow.  This last couple weeks has been dragging in anticipation of THE END!
1a, VL  1.05 Mil, ALT 47
Fibrosure F3 December 2014
Fibroscan F0-F1 March 2015
1995 INT & RYB -non-responder
2007 PEGIN & RYB 72 weeks tx - partial responder relapsed
1/23/15 Started Harvoni 12 weeks, EOT 4/17
2 week blood work -  <15 Und. (ALT 25)
4 week blood work - <15 Und. (ALT 29)
2/20/15 added RYB (4 weeks into 12 of tx)
8 week blood work - <15 Und. (ALT 23)
(EOT) 12 week blood work - <15 Und.
4wk POST tx VL - Und. (ALT16, AST 17)

Offline MEG

  • Member
  • Posts: 304
Re: Upcoming International Liver Congress in Vienna/
« Reply #6 on: April 11, 2015, 06:15:39 pm »
Indeed, it does seem to be moving slower. Like watching paint dry. ;-)

My(our?) challenge will be the 4 weeks before first EOT labs.  I wish I could go on a vacation where internet service and clocks don't exist.  As it is, since I'm beginning to feel better, in ever so small increments, my plan is to keep busy building back my strength---the combined sinusitis/antibiotic induced tendinitis/profound fatigue during this treatment is a testament to H's strength. 8 week on treatment viral load is undetectable...Incredible. I've considered my immune system MIA...
Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.

 


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