Welcome, Guest. Please login or register.
April 26, 2024, 08:30:17 am

Login with username, password and session length


Members
  • Total Members: 6307
  • Latest: golfer
Stats
  • Total Posts: 55126
  • Total Topics: 4851
  • Online Today: 134
  • Online Ever: 1314
  • (June 22, 2016, 05:23:42 am)
Users Online
Users: 0
Guests: 117
Total: 117

Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.
  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.
  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.
  • Product advertisement (including links); banners; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from the Hep Forum Moderators.
Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: COBAS® TaqMan® TEST  (Read 5763 times)

0 Members and 1 Guest are viewing this topic.

Offline jakas

  • Member
  • Posts: 265
COBAS® TaqMan® TEST
« on: March 04, 2016, 04:49:33 am »
This is the test I went for the VL AFTER END OF TREATMENT  am I right to assume that the lowest detection is 25 IU/mL ??

COBAS® TaqMan® HCV Test

Hepatitis C virus (HCV) viral load testing quantification
An in vitro nucleic acid amplification test for the quantitation of HCV RNA genotypes 1 through 6 in human serum or plasma.
 
The High Pure System Viral Nucleic Acid Kit allows manual specimen preparation and the COBAS® TaqMan® 48 Analyzer automates amplification and detection. This test utilizes realtime PCR technology for the detection and quantitation of HCV RNA.

Features and Benefits
 
Features
CE-IVD: Sensitivity (LOD; genotype 1) –  plasma: 9.3 HCV RNA IU/mL, serum: 8.8 HCV RNA IU/mL; linear range –  25 to 3.91×10^8 IU/mL

FDA-IVD: Sensitivity (LoD; across all genotypes) – 20 IU/mL; Linear range –Quantitation of HCV RNA from 25 to 3×10^8 IU/mL
COBAS® TaqMan® 48 Analyzer for automated real-time PCR amplification and detection

Benefits
Minimizes testing errors and manual intervention steps with automated closed-tube amplification and detection on the COBAS® TaqMan® 48 Analyzer
Improves result integrity with bar coded samples for sample tracking – AmpErase enzyme reduces risk of contamination – internal quantitation standard eliminates need for calibration
M/57 yrs.
Contracted (Unknown) 10-20-30 yrs back ??
Treatment Naive
Geno 1a&1b
VL  17+ million
ALT 200+, AST 170+
Fibroscan F4 ( 26+ kpa ) on 8th Dec. 2105
Started Tx 11th Dec.2015 ( 12 wks. Gilead Harvoni)
7/1/2016 :Viral Load|<25 UND.
23/1/2016: ALT 34 , AST 35, ALP 143
8 week NO labs done
EOT:03.03.2016 ( 84 pills eaten )
ALT 26, ALP 124, BIL .54
V/L <25 UND E.O.T.
4 weeks E.O.T. V/L UND::: SVR 4
SVR 12 and  SVR 24 on 16/8/16
Fibro 24.5kpa 23/05/16
SVR 63 05/17
Fibro 17.03.2020 kpa 6.3

Offline lporterrn

  • Member
  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: COBAS® TaqMan® TEST
« Reply #1 on: March 04, 2016, 04:46:22 pm »
You are correct
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

 


© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.