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Author Topic: AST and ALT slowly elevating  (Read 7714 times)

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Offline Tlk60

  • Member
  • Posts: 37
AST and ALT slowly elevating
« on: February 06, 2017, 08:36:04 pm »
Hey guys:
I finished my 8-week treatment with Harvoni and 5 weeks in I was undetected.  My AST and ALT were 26 and 22...yippee...down from the upper 40s.  My family doctor ordered some routine blood work last week and I noticed my AST and ALT numbers were creeping back up...33 and 27...  I have not had my 12 week post treatment labs done yet...that comes next month. I was just wondering if I should be concerned?  These numbers are still within the normal range but still several points higher than last month.  Anyone else have this happen?  Am I not really undetected??

Offline andrew90

  • Member
  • Posts: 71
Re: AST and ALT slowly elevating
« Reply #1 on: February 06, 2017, 09:23:23 pm »
i believe those numbers can fluctuate some what. if u were undetected by 5 weeks im sure your fine, 8 week treatment means your VL was low. did you go to the same lab as for your blood test drawn from family doctor? different machinery values could be a thing too.
« Last Edit: February 06, 2017, 09:25:45 pm by andrew90 »
5/1/17 UNDETECTED!

EOT Blood Testing 1/25/17
UNDETECTED!

Five week blood testing 12/8/16
DETECTED
Viral Load: 35(IU/mL)
AST: 34

Started Epclusa 10/2/16

Genotype 3a

9/19/16
Fibrosis: F2/3
ALT: 459
AST: 189
Viral Load: 6415894 (iU)/mL

Offline lporterrn

  • Member
  • Posts: 1,969
  • LucindaPorterRN
    • LucindaPorterRN
Re: AST and ALT slowly elevating
« Reply #2 on: February 06, 2017, 09:54:52 pm »
Andrew is right. Also, if you had any alcohol or a med or certain supplements, these can raise the numbers.
Lucinda Porter, RN
1988 Contracted HCV
1997 Interferon nonresponder
2003 PEG + ribavirin responder-relapser
2013 Cured (Harvoni + ribavirin clinical trial)
https://www.hepmag.com/blogger/lucindakporter

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,545
  • Get tested, get treated, get cured, fight Hep c!
Re: AST and ALT slowly elevating
« Reply #3 on: February 07, 2017, 04:52:25 am »
As long as they are normal I wouldn't worry. Normal is normal that is why it is a range anywhere in normal range is good as another
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Tlk60

  • Member
  • Posts: 37
Re: AST and ALT slowly elevating
« Reply #4 on: February 07, 2017, 11:33:50 am »
Thanks everyone....You really put my mind at ease.  I am a worrier...that's just what I do and I am pretty good at it. tee hee

I was never a big drinker and once I was given the opportunity to take Harvoni, I decided I wouldn't drink at all anymore...I am so grateful to have the chance to be free of the virus that I am overly cautious regarding my liver now. So alcohol couldn't be the culprit.

I also put on about 13 pounds in the eight weeks I was on Harvoni.  I am not blaming the drug...it was purely my bad eating habits.  Not sure if that could be it as well???

I did go to the same lab as my previous tests BUT I did remember  that 2 weeks after completing my Harvoni treatment, I resumed taking my Crestor for high cholesterol. I am wondering if that is what made the slight elevation???

Offline Lynn K

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  • Get tested, get treated, get cured, fight Hep c!
Re: AST and ALT slowly elevating
« Reply #5 on: February 07, 2017, 06:34:14 pm »
So what you have is not an elevation you are in normal range so it is just a statistical variation within normal range.

That being said per the Mayo Clinic some things that can raise liver enzymes are

Certain prescription medications, including statin drugs used to control cholesterol
Drinking alcohol
Heart failure
Hepatitis A
Hepatitis B
Hepatitis C
Nonalcoholic fatty liver disease
Obesity
Over-the-counter pain medications, particularly acetaminophen (Tylenol, others)

They are talking about causes for above normal test results.

So about you question could it have been going back on Crestor? Maybe, maybe not. Doesn't matter though your results are normal

But really your results can change every day. A blood test is just a snapshot in time at that precise moment it will vary from day to day.

Suppose your earlier result was the higher one and the later one was the lower. Either way it does not mean anything as both results are normal.
« Last Edit: February 07, 2017, 06:37:15 pm by Lynn K »
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

 


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