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Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

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Recent Posts

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1
Hepatitis B / Re: Tested for HBV and wife pregnant. Please help
« Last post by Lynn K on January 17, 2022, 10:02:29 pm »
“ A result of "<10 IU/mL (<1.00 log IU/mL)" indicates that HBV DNA is detected, but the HBV DNA level present cannot be quantified accurately below this lower limit of quantification of this assay. When clinically indicated, follow-up testing with this assay is recommended in 1 to 2 months.”

https://www.mayocliniclabs.com/test-catalog/overview/65555#Clinical-and-Interpretive
2
Hepatitis B / Re: Tested for HBV and wife pregnant. Please help
« Last post by Lynn K on January 17, 2022, 12:48:29 pm »
Here is a link to FAQ for the general public about hepatitis B from the US CDC

https://www.cdc.gov/hepatitis/hbv/bfaq.htm#bFAQc01
3
Hepatitis B / Re: Tested for HBV and wife pregnant. Please help
« Last post by Lynn K on January 17, 2022, 12:32:45 pm »
We here are a community of patients and cannot offer medical advice or guidance. We are here to provide moral support and to share our own experiences.

The virus would not be in your DNA. The test you listed is a test for the DNA of the hepatitis B virus. It does appear to me as a non medical person that test does show as weakly positive for hepatitis B virus DNA.

For medical advice and recommendations follow the advice of your personal physician. Of course if you are not confident in the advice of your current doctor you may seek a second opinion. I’m assuming the doctor would prescribe the standard vaccination protocols for your baby.

Congrats on you soon to be born addition to your family.

Here is a link to the immunization schedule for children through adolescent per the US CDC

https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html



4
Hepatitis B / Tested for HBV and wife pregnant. Please help
« Last post by concerned2022 on January 15, 2022, 11:08:58 pm »
Hello,

Please kindly read my situation. I’m concerned as my wife is pregnant and I’m worried about the baby.

I’m 35 years old who grew up in South Asia. I never had any blood work or annul checkups done until recently. I did not even know my blood group. No sexual partners other than my wife. I don’t know how or when I might have got Hep B.

We came to know that my wife was pregnant in Oct 2021. No sex after she got pregnant. I went for blood donation drive at American Red Cross in Nov 2021 and got a letter with below test results:

Hepatitis B Surface Antigen Test: Non-Reactive
Hepatitis B Core Antibodies Test: Reactive
HBc Final Interpretation: Reactive
HBV Discriminatory NAT: Reactive

I went to Primary Physician and test reports from that visit:

Hepatitis B Surface Antigen: Non-Reactive
Hepatitis B Core IGM: Non-Reactive
Hepatitis C Virus Antibody: Non-Reactive
Hepatitis A Antibody IGM: Non-Reactive

Doctor said that lab made a mistake in above tests and did wrong test(like Hep C & Hep A instead of Hep B tests). But he said it doesn’t matter as virus was found in my DNA(though very low) as per below results from another report. He has referred me to a GI. I have to see GI next.

HBV QNT by NAAT(IU/ml): <10 detected
HBV QNT by NAAT(log IU/ml): <1.00

My wife’s blood work from her Obgyn’s first prenatal visit tested Non-Reactive for HBsAg.

I’m confused to whether I have Hep B and if I can infect my wife?

Going forward, what tests/vaccinations should we follow for my wife through her pregnancy and for baby when born ?
5
People with acute or recently acquired hepatitis C who received a six-week course of Epclusa (sofosbuvir/velpatasivir) were more likely to relapse and less likely to be cured than those treated for 12 weeks, according to results from the REACT trial.

The advent of direct-acting antivirals has made hepatitis C treatment shorter, better tolerated and much more effective than previous interferon-based therapy. The typical course of treatment for chronic hepatitis C virus (HCV) infection now ranges from eight weeks of Mavyret (glecaprevir/pibrentasvir) for previously untreated people to 12 weeks of Mavyret, Epclusa or Harvoni (sofosbuvir/ledipasvir) for most treatment-experienced patients.

Read more:
https://www.hepmag.com/article/six-weeks-may-enough-early-hepatitis-c-treatment
6
Successful treatment of hepatitis C virus (HCV) led to improvement in cognitive function in people with and without liver cirrhosis, according to study results published in the European Journal of Neurology.

“These data indicate that HCV-associated cognitive impairment may be a reversible component of cognitive decline and may constitute an indication of treatment independently of the stage of liver disease,” wrote the researchers.

Chronic hepatitis C can lead to severe liver complications, including cirrhosis and liver cancer, but it has also been linked to other conditions, including neuropsychiatric problems that affect daily functioning and health-related quality of life (HRQoL). Learning, memory, attention, executive function and visual-spatial ability are some of the cognitive functions that may be adversely affected. But whether hep C treatment can reverse these complications is not well understood.

Read more:
https://www.hepmag.com/article/curing-hepatitis-c-improves-cognitive-function-quality-life
7
An eConsult service that treats people with hepatitis C virus (HCV) in a primary care clinic saw cure rates similar to those of independent primary care, according to findings published in the Journal of Viral Hepatitis.

“This study demonstrates that the implementation of an electronic consultation system aimed to support primary care physicians to treat HCV without requiring specialty involvement in care is an effective intervention to cure HCV within a large urban safety net health system,” wrote Jacey Nishiguchi, PharmD, of the San Francisco Department of Public Health, and colleagues.

Read more:
https://www.hepmag.com/article/primary-care-expert-consultation-successful-treating-hepatitis-c
8
I Just Tested Positive for Hepatitis C / Re: tested positive, first post
« Last post by Lynn K on September 10, 2021, 03:01:32 pm »
Great to hear from you! Hey man hakuna matata no worries the past is gone and behind you today is a gift what’s important is how you are today and every day after ;)

Now go forward and enjoy your hep C free life
9
I Just Tested Positive for Hepatitis C / Re: tested positive, first post
« Last post by holy$h!T on September 10, 2021, 01:10:46 pm »
Hello to everyone viewing this forum, and thanks to Lynn, Kim, Mugwump, and all others who offered input during a difficult time.

On September 08, 2021 blood test results showed:
HCV RNA PCR Not Detected
ast 23
alt 15

ast/alt history from October 27, 2016 through September 08, 2021
ast  41   70   54   69   45  32  31   36   23
alt   35   67   57   71   42  19  19   17   15
10
On Hepatitis C Treatment / Re: Vosevi
« Last post by Lynn K on September 01, 2021, 03:17:28 pm »
Hi gr8in Tx

I treated a total of 5 times. Three with the old interferon based regimens. I was a null responder to those no change in viral load.

When the new DAA’s were first approved I treated with Sovaldi and Olysio off label usage for 12 weeks but I was found to have relapsed 12 weeks after finishing treatment. Then Harvoni was approved in October 2014. My Dr prescribed me 24 weeks of Harvoni with Ribavirin. That was my last treatment I was finally cured.

Long way of saying if I can be cured I’m very confident you will be too. As Jack says please check back and let us know your 12 weeks post treatment results that’s the one for all the marbles!

Good luck!
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