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Welcome to the Hep Forums, a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.
  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.
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Recent Posts

Pages: [1] 2 3 ... 10
1
Considering Hepatitis C Treatment / Closing the Hepatitis C Treatment Gap
« Last post by iana5252 on December 18, 2024, 10:46:06 am »
Rachel Melson, DNP, FNP-C, has a tale to tell. The nurse practitioner is the director of the outreach clinic at Swope Health in Kansas City, Missouri. Her tale provides insight into why, according to the Centers for Disease Control and Prevention, in 2022 only one in three people diagnosed with hepatitis C virus (HCV) received treatment within 12 months of their diagnosis. And this, even though for the past decade, a new era of hep C treatment not only cures the vast majority of people but is also almost completely free of side effects.

Swope Health treats many people who are currently or formerly homeless or have experienced imprisonment and drug use. Recently, says Melson, a nurse on her staff spent 35 minutes on the phone with an insurance company trying to get prior authorization to cover someone’s HCV treatment. Insurers often set high barriers for the treatment, which costs tens of thousands of dollars per course.

Read more...
https://www.hepmag.com/article/closing-hepatitis-c-treatment-gap
2
Metabolic dysfunction-associated steatohepatitis (MASH) / Novel Thyroid Hormone Receptor Agonists Show Promise for MASH
« Last post by iana5252 on December 18, 2024, 10:44:55 am »
Two experimental thyroid hormone receptor agonists, VK2089 and ALG-055009, led to significant improvements in people with metabolic dysfunction-associated steatohepatitis (MASH), according to late-breaking study results presented at the American Association for the Study of Liver Diseases Liver Meeting 2024.

One study showed that up to 75% of people treated with VK2809, from Viking Therapeutics, achieved MASH resolution with no worsening of liver fibrosis at 52 weeks. In another study, Aligos Therapeutics’ ALG-055009 led to a reduction in liver fat at 12 weeks, supporting further evaluation.

Read more...
https://www.hepmag.com/article/novel-thyroid-hormone-receptor-agonists-show-promise-mash
3
Metabolic dysfunction-associated steatohepatitis (MASH) / FDA Approves First-Ever Drug for Fatty Liver Disease
« Last post by iana5252 on December 09, 2024, 10:40:52 am »
On March 14, the Food and Drug Administration (FDA) granted accelerated approval of Madrigal Pharmaceuticals’ resmetirom (brand name Rezdiffra) as the first medication for metabolic dysfunction-associated steatohepatitis (MASH), or advanced fatty liver disease.

Resmetirom, a once-daily pill, was approved along with diet and exercise for adults with MASH who have moderate to advanced (Stage F2 or F3) liver fibrosis but have not yet progressed to cirrhosis (Stage F4). Patients will not need a liver biopsy to be eligible for the new treatment. The approval is supported by results from a late-stage clinical trial which showed that resmetirom is the first drug to both reduce liver fat accumulation and improve fibrosis.

Read more...
https://www.hepmag.com/article/fda-approves-firstever-drug-fatty-liver-disease
4
Metabolic dysfunction-associated steatohepatitis (MASH) / Novel Thyroid Hormone Receptor Agonists Show Promise for MASH
« Last post by iana5252 on December 09, 2024, 10:30:18 am »
Two experimental thyroid hormone receptor agonists, VK2089 and ALG-055009, led to significant improvements in people with metabolic dysfunction-associated steatohepatitis (MASH), according to late-breaking study results presented at the American Association for the Study of Liver Diseases Liver Meeting 2024.

One study showed that up to 75% of people treated with VK2809, from Viking Therapeutics, achieved MASH resolution with no worsening of liver fibrosis at 52 weeks. In another study, Aligos Therapeutics’ ALG-055009 led to a reduction in liver fat at 12 weeks, supporting further evaluation.

Read more...
https://www.hepmag.com/article/novel-thyroid-hormone-receptor-agonists-show-promise-mash
5
Post Hepatitis C Treatment / Re: Third time may be the charm this time - Finished 12 weeks of Vosevi!
« Last post by jberlin on October 13, 2024, 08:26:17 am »
Annie,

I (and all of us here) am so happy for you and enjoyed being on your final victory lap with you. It was a long journey and so glad you shared it.

Best wishes,
jack
6
Post Hepatitis C Treatment / Re: Third time may be the charm this time - Finished 12 weeks of Vosevi!
« Last post by Lynn K on October 07, 2024, 10:07:09 pm »
No problem so happy for you.❤️
7
Post Hepatitis C Treatment / Re: Third time may be the charm this time - Finished 12 weeks of Vosevi!
« Last post by opaleye on October 07, 2024, 04:54:02 pm »
Hi Jack and Lynn,

Sorry it's been so long since I've checked in. Thank you both for being there for me during this long and winding road. I sincerely hope my story helps others like your stories have helped me.

Best of everything,
Annie
8
Post Hepatitis C Treatment / Re: Third time may be the charm this time - Finished 12 weeks of Vosevi!
« Last post by Lynn K on June 22, 2024, 08:18:19 pm »
Annie

Congrats, I’m so very happy for you!!

I still tracked the day I finished my 5th and final treatment kind of a personal holiday of rebirth for me

What a relief for you and all of us finally being able to say we are free!

Best to you
Lynn
9
Post Hepatitis C Treatment / Re: Third time may be the charm this time - Finished 12 weeks of Vosevi!
« Last post by jberlin on June 22, 2024, 02:49:02 pm »
Annie,

OMG! I started getting worried as the days passed. I am so happy for you. Ecstatic!

What a battle! What a warrior you are! I remember sitting in my car crying my eyes out when I got the news and I only went through two treatments!

Your story will help others, and your response here made my day! Woohoo!

Make the rest of your life count Annie... Best wishes!

jack
10
Post Hepatitis C Treatment / Re: Third time may be the charm this time - Finished 12 weeks of Vosevi!
« Last post by opaleye on June 22, 2024, 02:36:29 pm »
Hi Jack!

There was a delay in me getting the lab order, so I just got my final viral load test results in this morning.

Not Detected!!!!!!!!!!! I AM CURED!!!!!!

Tears of joy. I wasn't sure I would ever get here. The dragon is slayed!!!

Thank you so much for all of your encouragement, good wishes, and fingers and toes crossing. I so appreciate you sharing your experiences and wisdom that only comes from one who has been on this journey before and at last reached this destination.

I hope my journey gives others hope that even for previous non-responders, a cure is possible.

Best of everything,
Annie
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