Welcome, Guest. Please login or register.
February 25, 2024, 10:43:39 am

Login with username, password and session length


Members
  • Total Members: 6307
  • Latest: golfer
Stats
  • Total Posts: 55121
  • Total Topics: 4850
  • Online Today: 148
  • Online Ever: 1314
  • (June 22, 2016, 05:23:42 am)
Users Online
Users: 0
Guests: 68
Total: 68

Welcome

Welcome to the Hep Forums, a round-the-clock discussion area for people who have Fatty Liver Disease, Hepatitis B, C or a co-infection, their friends and family and others with questions about hepatitis and liver health. Check in frequently to read what others have to say, post your comments, and hopefully learn more about how you can reach your own health goals.

Privacy Warning: Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.
  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.
  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.
  • Product advertisement (including links); banners; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from the Hep Forum Moderators.
Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: After tx (POST) 4wk or 12 wk SVR results (Harvoni only) - CHECK IN HERE PLEASE!  (Read 703357 times)

0 Members and 3 Guests are viewing this topic.

Offline Bob V

  • Member
  • Posts: 231
John
Sending good vibes your way.
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Junkyard

  • Member
  • Posts: 24
Lynn,
4wk vl und. That's the great news

Offline Mugwump

  • Member
  • Posts: 778
  • My number of posts means nothing, piscor ergo sum!
Kate it is time to attack a chocolate cake. Well at least a small one! I know when my 12 week comes in I will do something special for every single person who has helped me through this nightmare. THIS MAKES ME HAPPY HEARING SOMEONE WHO relapsed with 1a has made the 12 week UND!

Cheers and tears
Eric

Caution shameless self promotion below :-)
https://www.hepmag.com/article/eric-reesor-27742-782589663
DING DONG MY DRAGON (HCV) IS FINALLY DEAD!

Offline Bob V

  • Member
  • Posts: 231
Kate it is time to attack a chocolate cake. Well at least a small one! I know when my 12 week comes in I will do something special for every single person who has helped me through this nightmare. THIS MAKES ME HAPPY HEARING SOMEONE WHO relapsed with 1a has made the 12 week UND!

Cheers and tears
Eric
-----------
Eric
Chocolate cake sounds SO good :)
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline kate0b1

  • Member
  • Posts: 293
thanks guys, it feels so great and a little surreal to finally say it "i HAD hepc". @Eric, if i gain any more weight from this i will need a whole new wardrobe. I am actually hoping that i can see a piece of chocolate and not eat it finally.

stay well everyone, and thanks for holding my hand through this  :)

kate

Offline Long_Haul

  • Member
  • Posts: 161
  • Slayed the Dragon
AWESOME Kate! You made it and I hope I'm right behind you.  So happy to hear you got through. Take care of yourself and enjoy the victory and  have a long enjoyable life with your family. 12WK SVR test for me next Friday.

John, so sorry to hear your news, hang in there!  They are getting the better of HCV with new treatment approaches. You will get there soon, keep plugging away at beating the virus. Best wishes.

AL
Genotype 1A

Diagnosed 1989
Biopsy-cirrhosis stage 4 2000, no starting VL this round

3 rounds of Int+Rib
(Combo/48wks,Peg/26 Wks,Triple with Incivek/16wks)
UND with Incivek, Relapsed
Started 12 weeks Harvoni and Rib Jan 2nd,2015
4 weeks Undetected
8 weeks Undetected!
EOT at 12 weeks Undetected
EOT at 24 weeks STILL UNDETECTED
Completed TX Mar 26th,2015

EOT plus 4 weeks UNDETECTED
EOT plus 12 weeks UNDETECTED !!!!!!!!!!! I am DONE!

NO LONGER a member of the "WAITING GANG"

Offline DeeDee

  • Member
  • Posts: 30
59 yr female genotype 1B
probably contracted blood transfusion in 1980
started Harvoni treatment 01/10/15 and completed the 8 weeks on 03/06/15
My test showed I had 15 out of 2,017,239 after treatment
Recent test: 05/15/15
Component Latest Ref Rng 5/15/2015
ALBUMIN 3.8 - 5.0 g/dL 4.1
AST 10 - 35 U/L 17
ALKALINE PHOSPHATASE 0 - 153 U/L 89
ALT 10 - 35 U/L 14
BILIRUBIN 0.3 - 1.3 mg/dL 0.3
BILIRUBIN, DIRECT 0 - 0.3 mg/dL <0.2
PROTEIN 6.0 - 8.3 g/dL 7.2
HCV RNA HCVXD IU/mL HCV RNA NOT DETECTED
HCV RNA COMMENTS ::::::::::::::::::::::::::::::::::::::::

Offline Bob V

  • Member
  • Posts: 231
DeeDee
Congrats!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Hepcbgone

  • Member
  • Posts: 3
1. 4wk - 12 wk EOT VL status-4 Week-Undetected
2. Treatment duration-24-Weeks                                                                                                              3. tx naive or experienced-Naive
4. Genotype (1a or 1b)-1a
5. F1-F4 fibrosis status (date)-F2-1/1/2014
6. Initial VL (date)-6 Million +


Offline Bob V

  • Member
  • Posts: 231
Hepcbgone

Congrats to you too.
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline DeeDee

  • Member
  • Posts: 30
Congrats  Bob V & Hepcbgone :)

I forgot to mention:

My FibroSpect was F0-F1 index 9

Sonogram Impression- Normal liver in size/shape and positioned with no space-occupying lesions or dilatation of the biliary tree. 

Offline Bob V

  • Member
  • Posts: 231
Hi Guys

My brother was also on Harvoni, his HepC profile was almost identical to mine EXCEPT he had GT-1B.

He also reached SVR 12, so another successful Harvoni patient.
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline MEG

  • Member
  • Posts: 304
Hi all,

I'm just getting the opportunity to check in with everyone---it's been too long....

So wonderful---beyond words actually---to see all of you who are achieving SVR....I'll be testing 12 weeks POST EOT in July.

But for our friends here who have relapsed---I am so sorry. We hurt with you. Huge hugs and know that as hard as this is right now that you will rise again to fight this virus. For now, let yourself feel what you're feeling and come over here any time. There are lots of wonderfully broad shoulders here...Meg.
Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.

Offline MYCACHE

  • Newbie
  • Posts: 2
1. UD 4wk during treatment. 12wk EOT Relapse VL 100,000
2. 8 weeks
3. tx naive
4. Genotype (1a)
5. F1 01/01/2014
6. Initial VL 100,000 12/1/2013

Trying to decide if I should retreat for 24 weeks or wait for new treatment.

Offline Katie

  • Member
  • Posts: 784
Mycache...so sorry to hear that.  The research has made this great breakthrough and they are constantly improving with new treatments on the horizon.  Good luck to you in the future and you will go forward and be cured.

We all ache inside every time someone's treatment fails.  You aren't alone.

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline dragonslayer

  • Member
  • Posts: 873
MyCache.... Really sorry about your results.. Like Katie said, it effects us all when this happens.  Did you have any on-treatment or post-treatment viral loads drawn other than 4 wks into treatment, and 12 wks post treatment?

I think studies show an 80% svr rate when 8 wk Harvoni treatment failures get retreated with 24 wks of Harvoni.  Or, you might wait for the next treatments to come online which will have somewhat better odds.

Keep us apprised.
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Bob V

  • Member
  • Posts: 231
Mycache
So sorry to hear this, it really sucks. Like Katie and Paul posted there's some new meds coming. As for retreating with Harvoni if Paul is correct at 80% not sure I would do it.

Best of luck moving forward.

**Just to be clear this lab is 12wks post tx ?
« Last Edit: June 17, 2015, 12:20:17 am by Bob V »
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline MYCACHE

  • Newbie
  • Posts: 2
Yes.. I completed treatment 1/31/2015 and had post treatment labs on 6/5/2015.  VL was back to where it was pretreatment along with AST and ALT levels. Thanks for all the kind encouragement.. 

Linda

Offline TerryLF

  • Member
  • Posts: 9
Unfortunately, I know how it feels to have the treatment not work. I was VL 120 two weeks post-treatment. My doctor just said to start  coming in every six months to check my liver function, he said that is all, no other way to go. I have no option for longer treatment, I am having other problems that prevent me form working full-time so I get Illinois Medicaid and you only get one chance in a lifetime for treatment. I may have a chance if I am approved for disability and I get Medicare, I don't know. My problem is that I have known for two years now that I have cirrhosis, and I have some problems associated with that. I am going to try and get my doctor to do another RNA test in a few months to make sure, but I don't know if I will be allowed to do that. I think Harvoni should up the treatment to 24 weeks for all people who have cirrhosis, treatment naive or not. I guess we'll see.

Offline Katie

  • Member
  • Posts: 784
Hi Terry,  Please encourage your doctor to check your VL again at 12 weeks post tx.  There have been several of us who cleared after being detected at EOT and another who appeared to relapse and cleared.  Even if you didn't succeed, at least you'd know for sure.

It is a hard blow to receive that news, and I send you a big {{{HUGS}}}!

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline hope4cure

  • Member
  • Posts: 19
8 week treatment
naive
post 12 weeks as of 6/11/15
Cured!



Offline mario555

  • Member
  • Posts: 226
Hope4cure. Super! Happy for you! Enjoy the rest of your life without this dreaded disease...
60 years old. Likely infected 1975. Geno 1a
F4  8 millions VL,  AST 140  ALT 140
Generally in good health except problems are creeping up rapidly!
2 failed attempts Inf 2000 and Inf-riba 2010
Harvoni 24 weeks
Start 11/13/2014   EOT 4/27/2015
VL2 - UND
VL4 - UND (may 25)
VL12 - UND
VK24 -  UND
Hopefully cured forever!

Offline hope4cure

  • Member
  • Posts: 19
Thank you and seeing how I have had it since birth (32 years) it is truly awesome.

Offline Bob V

  • Member
  • Posts: 231
Hope4cure
Like I posted on the other thread congrats!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline mdj

  • Member
  • Posts: 5
The latest data I see is from April 29--is there an update or is this all there is at the moment?

Offline TerryLF

  • Member
  • Posts: 9
Thanks for the replies everyone. I know this is for people 12 weeks , but I guess that is not how my doctor is handling this. He gave me a RNA test two weeks post-treatment and I guess that's it. I was UD 4 weeks into treatment and VL 120 two weeks post treatment. I will take the advice given here and push for a test at 12 weeks, hopefully I will be one of the ones who clear. I'll drop in in the future and let everybody know how it went. Thanks.

Offline Long_Haul

  • Member
  • Posts: 161
  • Slayed the Dragon
Best of luck Terry, push hard for the follow-up test and hang in there.

I just got notified by my PCP, 12 week SVR results are UNDETECTED.  The DRAGON is dead, the DRAGON is DEAD........... I know 24 week SVR is the real clincher, but I will take this as it is. I brought my gun to this knife fight and won! Thanks for all of the encouragement and advice along the way. I hope all those that are waiting get this wonderful news and those still treating, hang in there, you will make it.

Best wishes,

AL
Genotype 1A

Diagnosed 1989
Biopsy-cirrhosis stage 4 2000, no starting VL this round

3 rounds of Int+Rib
(Combo/48wks,Peg/26 Wks,Triple with Incivek/16wks)
UND with Incivek, Relapsed
Started 12 weeks Harvoni and Rib Jan 2nd,2015
4 weeks Undetected
8 weeks Undetected!
EOT at 12 weeks Undetected
EOT at 24 weeks STILL UNDETECTED
Completed TX Mar 26th,2015

EOT plus 4 weeks UNDETECTED
EOT plus 12 weeks UNDETECTED !!!!!!!!!!! I am DONE!

NO LONGER a member of the "WAITING GANG"

Offline Bob V

  • Member
  • Posts: 231
Al

Wonderful news, congrats!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Katie

  • Member
  • Posts: 784
Al, What WONDERFUL  NEWS !!!  You definitely get a High Steppin Happy Dance!
Have a wonderful life!

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline kate0b1

  • Member
  • Posts: 293
agh @Al, I have been waiting for this post  :-* :-* :-* :-*
I hope its sunny there today for you

kate

Offline Barbs

  • Member
  • Posts: 3
Just received results  ;D

1  12 week EOT status - undetectable
2. Treatment duration - 12 weeks Harvoni + Ribavirin
3. tx naive or experienced - tx experienced
4. Genotype (1a or 1b) - 1a
5. F1-F4 fibrosis status (date) - F2
6. Initial VL (date) - Nov 2014 - 1.8 million

Offline Bob V

  • Member
  • Posts: 231
Barbs

Congrats!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline anniemybaby

  • Member
  • Posts: 133
Harvoni for 8 wks just had my results for 3 month eot undetected will have one more test at the 6 month mark
Annie

Offline Bob V

  • Member
  • Posts: 231
Annie
I was hoping you'd post. Wonderful news, congrats!!!!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Long_Haul

  • Member
  • Posts: 161
  • Slayed the Dragon
Congratulations to Annie and Barb.   Thanks to Bob V, Katie, and Kate. I am already feeling a ton lighter. I'm not sure if it has really sunk in yet. Getting stronger every day and the respiratory depression is getting a bit better. I can now ride the bicycle without getting too winded. tinnitus is less, so I guess I am on the mend.

To everyone that has given me advice and support through treatment thank you so muck. The support on here is like no other. Those of you in treatment hang in there, there is hope and light at the end of the tunnel. I waited 40+ years to defeat the Dragon. It can and will be done!

Best wishes,

Al
Genotype 1A

Diagnosed 1989
Biopsy-cirrhosis stage 4 2000, no starting VL this round

3 rounds of Int+Rib
(Combo/48wks,Peg/26 Wks,Triple with Incivek/16wks)
UND with Incivek, Relapsed
Started 12 weeks Harvoni and Rib Jan 2nd,2015
4 weeks Undetected
8 weeks Undetected!
EOT at 12 weeks Undetected
EOT at 24 weeks STILL UNDETECTED
Completed TX Mar 26th,2015

EOT plus 4 weeks UNDETECTED
EOT plus 12 weeks UNDETECTED !!!!!!!!!!! I am DONE!

NO LONGER a member of the "WAITING GANG"

Offline amy1662

  • Member
  • Posts: 41
Hello Everyone, I posted this in another forum and am reposting here,  I just want to let everyone know I went to Doctors today to go over my post treatment blood work. I am genotype 1a. Stage one to stage two liver damage. I started Harvoni in December and was prescribed twelve weeks worth of the medication. My experience with Harvoni was not bad at all. I finished my last pill Febuary 22nd and had blood drawn June 9th. I was told by my doctor today that I am undetected and cured. My doctor told me that I know longer have the virus in my blood. He said I will always test positive because of the antibodies but I no longer have the virus. Whooohooo so happy. This was my second try at treatment the first was back in 2002 interferon and ribavirin for one year. I relapsed and decided to wait for something better. I believe I have been infected for over twenty years. I am glad to be done with this and can now move on with my life. My doctor told me the damage that was done to my liver is reversable and I should go back to stage zero over time. He wants to see me back in one year to see how my liver has healed now that I am cured. I want to wish everyone luck and hope all are cured from this terrible disease. Harvoni has gave me a new lease on life I know longer feel drained with brain fog. I can truly feel the difference between the old me and new. Have more energy. Thank you everyone, I hope my post gives others hope, there is a light at the end of the tunnel. :)

Offline Bob V

  • Member
  • Posts: 231
Yay Amy, congrats!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Mike

  • Member
  • Posts: 999
Congrats, Amy!

Time to celebrate your new life!

Best, best wishes, Mike
Genotype 1a
Treated 2001 with PEG and RIBV
Treated in 2014 SOL+PEG+RIBV
Cured July 2014

Offline amy1662

  • Member
  • Posts: 41
Thank you everyone, I am grateful for this forum and all its support. Going to give back and help others.  :)

Offline EleanorB

  • Member
  • Posts: 14
One more for the tally - UND 4weeks POT after 8 week Harvoni!
Hep C infection probably via transfusion 1976
Known positive since 2007
VL 500,000
Harvoni start date 3/13/15
UND as of 4/9/15 (4 weeks)

Offline Bob V

  • Member
  • Posts: 231
Eleanor
Congrats! Are you doing 12wk post labs too?
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Katie

  • Member
  • Posts: 784
I just got my recent results and I am Hep C FREE!  Totally delighted to no longer be a bio-hazard, and was one of the few who cleared AFTER being detected at EOT.  I am still not feeling well and would love to have my Harvoni energy back but I am sure I will improve with time. I actually feel worse in some ways than I did prior to treatment, only very different, and many things I had for over a decade are totally gone.  Good luck to all on this journey and keep the faith!

1. 16 week Post EOT  UNDETECTED
2. 8 wk Post EOT VL status - Undetected
3. Treatment duration - 12 wks
4. tx naive or experienced - tx naive
5. Genotype (1a or 1b) - 1a
6. F1-F4 fibrosis status (date) - no cirrhosis
7. Initial VL (date) - 2.6 mil
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline Bob V

  • Member
  • Posts: 231
Katie
Wonderful news, congrats! :)
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Katie

  • Member
  • Posts: 784
Thanks Bob.  You are always so supportive.  Best of luck to you and everyone on this forum.  We are the fortunate ones and we will be here for those still fighting the battle! Onward Warriors! 

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline Long_Haul

  • Member
  • Posts: 161
  • Slayed the Dragon
WOOOOHHHHHOOOOOOOO!, Awesome news Katie, you rock! Now you can move on from this and start getting a lot more energy.

Best wishes,  :) :) :)


AL
Genotype 1A

Diagnosed 1989
Biopsy-cirrhosis stage 4 2000, no starting VL this round

3 rounds of Int+Rib
(Combo/48wks,Peg/26 Wks,Triple with Incivek/16wks)
UND with Incivek, Relapsed
Started 12 weeks Harvoni and Rib Jan 2nd,2015
4 weeks Undetected
8 weeks Undetected!
EOT at 12 weeks Undetected
EOT at 24 weeks STILL UNDETECTED
Completed TX Mar 26th,2015

EOT plus 4 weeks UNDETECTED
EOT plus 12 weeks UNDETECTED !!!!!!!!!!! I am DONE!

NO LONGER a member of the "WAITING GANG"

Offline nicole_1234

  • Member
  • Posts: 134
KATIE!!!!!!! CONGRATS sister!!!!!!!!! So happy for you, that news made my day xo

nicole
Genotype 1a
TX interferon/riba 2007 (relapsed)

TX Harvoni 12 week start Dec 3 2014
Starting vl 650,000  ALT 55 AST 63
2 week  vl <15
4 week vl UND
8 week vl UND
12 week EOT ALT 11 AST 18
6 week post tx UND ALT 15 AST 20
12 week post tx UND (CURED!!!!) ALT 11 AST 20
24 week post tx UND ALT 11 AST 18

Offline dragonslayer

  • Member
  • Posts: 873
Katie,  I knew you would do it!  You must be elated.  I saw your announcement in another thread and commented there, but wanted to make sure youd see it!  CONTRATULATIONS!!!!!!!!!!!!!!!!

I go for my 24 wk test  in a couple of weeks.  Hope its just a formality!!
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Katie

  • Member
  • Posts: 784
You guys are all so great.  Thank you for all of your support these past 6 months. You all made my journey so much easier and I'll stay on this forum for awhile as I am addicted to it  :D and need to follow all of my friends and how their journey is going!

Have a fabulous weekend and enjoy each and every day!

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline kate0b1

  • Member
  • Posts: 293
hey katie, i am just seeing this, such a great day  ;D ;D I hope this finds you well, i am moving forward and starting to feel like I'm getting a handle on felling really well lol.

its so cool to see everyone getting to the finish line  :-* :-* :-*

kate

Offline ma snart

  • Member
  • Posts: 65
Just got Helen's 8 week post viral load, UNDETECTED!!!!!!!!!!
will be back with 12 weeks post results very soon and feeling very confident that she will now be cured...
Thanks to all here.
Helen 54 yr old female
Geno 1B since 84 from transfusion
started Harvoni on 11-22-14 with 8.5 million viral
After 8 days 933 viral and normal AST and ALT
Week 10 viral load  UNDETECTED
Week 17    detected 19
Week 18    detected 21
Week 20    UNDETECTED   Doctor did prescribe Ribavirin, but have not taken it yet as we are thinking that weeks 17,18 had to have been mishandled.
All other test have shown normal levels.
Week 21 results  on Tuesday 4-21
Week 4 post Harvoni 24 week plan UNDETECTED!!

Offline Bob V

  • Member
  • Posts: 231
ma snart
Great news!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline GLCII

  • Member
  • Posts: 127
Is it unusual for the AST and ALT to somewhat spike after tx?
I just got all the info on my 4wk EOT labs. My Ast has risen to 46 and ALT to 29. The last labs I did was before EOT about 1 week. My Ast was 38 and ALT was 25.
I hope this is not a precursor to something bad.
My vl was und and everything else seems to be coming back after 12 wks of riba and harvoni.
I plan to ask my dr about this as well.  This may be a long 7 weeks to wait

I'm glad you asked this question. I had some concerns after my 4 week post EOT came back with an elevated AST of 35 up from 19 4 weeks ago. After reading some of the resonses and searching online, I feel better. My ALT only went up to 23 from 21 so that's good. When the main test comes in, i'll come back and post the results to add to Charly8's stats.
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline Karen3717

  • Member
  • Posts: 28
Congrats to all of you out there who are Hep C Free now!!!  I just got my 4 week EOT results back.....UNDETECTED!!!  This feels so amazing.  I know I still have one more hurdle at 12 weeks, so I am cautiously optimistic.  I haven't been this happy about anything in years.  Talk about cause for celebration on this wonderful July 4th.  Happy holiday to all of you!   
Transfusion 1982; Multiple accidental needlesticks; healthcare worker
(+) HCV antibody 1991
Genotype 1a
2001-Pegintron/Ribavirin 48 wks. Relapse 2mo post tx
2015-VL 316,000
Fibrosure-F2
Started Harvoni 3/13/15
2 weeks:  HCV PCR <15-DETECTED
4 weeks: HCV PCR <15-DETECTED
8 weeks: HCV PCR <15-DETECTED
12 weeks:  HCV PCR: NOT DETECTED!
4 Weeks EOT: HCV PCR:  NOT DETECTED!
12 Week post TX:  HCV PCR NOT DETECTED!

Offline Bob V

  • Member
  • Posts: 231
Karen2717 and GLCII

Great News! Enjoy the 4th.
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline DeeDee

  • Member
  • Posts: 30
Hello Everyone

12 week check in - UNDETECTED

ALBUMIN   3.8 - 5.0 g/dL   4.2   
AST   10 - 35 U/L   23   
ALKALINE PHOSPHATASE   0 - 153 U/L   90   
ALT   10 - 35 U/L   14   
BILIRUBIN   0.3 - 1.3 mg/dL   0.6   
BILIRUBIN, DIRECT   0 - 0.3 mg/dL   <0.2   
PROTEIN   6.0 - 8.3 g/dL   7.2

Offline Bob V

  • Member
  • Posts: 231
DeeDee
CONGRATS!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline DeeDee

  • Member
  • Posts: 30
Thanks Bob V

Doctor said 3 months if undetected he will consider it "Cured"

I am very happy at seeing others good reports

Offline coloradogirl

  • Member
  • Posts: 70
I was skeptical about my status, and cryed a lot after the last pill and the half-life of the drug wore off at about 72 hours after last dose. I woke up with those old familiar night sweats! I thought for sure the beast had returned, like it did the last time I came off treatment. Well, just pinch me ! My test 4 weeks post treatment are Undetected!  And the swollen feeling in my abs are gone and now I am sleeping through the last 3 days in a row. I'm so happy I was wrong about those night sweats. Amen!
HCV 1a diag 2002
1st tx 2004 null responder
2nd tx 2010 clinical trial relapsed
Last biopsy 2010 F2-F3
Fibrosure inconclusive some parameters out of range
Abdominal Ultrasound 7/2015 - No sign of Cirrhosis
Pretreatment  vl 580,000
Started Harvoni 3/2/2015 EOT: 5/24/2015
4th week 3/27/2015 vl < 5.3 Undetected
8th week 4/23/2015 vl <5.3 Undetected
12 week EOT  5/28/2015 vl <5.3 Undetected
4wk after tx 6/26/2015 vl <5.3 Undetected
12wk after tx 8/19/2015 vl<15 Undetected!!!
I'm Cured! Yes!

Offline KimInTheForest

  • Member
  • Posts: 1,972
  • Believe in yourself
Congrats Coloradogirl! Way to go! :)

kim
Kim Goldberg (Nanaimo, BC)
1970s: Contracted HCV (genotype 3a)
2015: Cured with Harvoni + ribavirin (12 weeks)
MY STORY: https://pigsquash.wordpress.com/2016/01/28/undetectable-my-hep-c-story/

Offline Katie

  • Member
  • Posts: 784
All this good news is a way to celebrate our Independence from Hep C; the alien parasitic virus.  Congratulations to all undetected warriors, and for those who didn't make the grade this time around, we are all here for you!  There is something just around the corner and you too will be free!

So happy for  you DeeDee and Colorado  Girl!

The fireworks has new meaning for many of us tonight!

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline GLCII

  • Member
  • Posts: 127
Thanks Bob V

But no congrats yet. I have all the tests back except the main test. I'll know that one monday. But after looking at my other labs, it's looking pretty good.  :)

And Congratulations to DeeDee, Karen3717 & Coloradogir!!!   :) It has to be a Great feeling knowing that after 4 weeks the virus is still gone. DeeDee It has to be an Amazing feeling after 12 weeks and being Undetected.  ;D

I never put much thought in to these EOT tests while treating but waiting for these EOT tests to come to back sure does come with a certain amount of anxiousness. Time is just dragging.
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline Bob V

  • Member
  • Posts: 231
Congrats Coloradogirl!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline GLCII

  • Member
  • Posts: 127
Finally undetected for more then 2 weeks after 3 previously failed treatments which included 3 liver biopsies, 4 ultrasounds, God only knows how many blood draws, 7530 Riba pills, 492 shots of interferon & 14 Procrit injections.

After all that, it was 84 pills that has had the most success so far.


1. 4wk - 12 wk EOT VL status / 4 Week Post EOT (Undetected)
2. Treatment duration /            12 Week
3. tx naive or experienced /      3x Experienced
4. Genotype (1a or 1b) /           1a
5. F1-F4 fibrosis status (date)/  F2-F3
6. Initial VL /                           2/17/14 VL 12043488
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline Karen1124

  • Member
  • Posts: 76
12 week post treatment Relapse! VL 424,000
8 wks Harvoni
Moderate fibrosis
Geno 1a
Geno 1a
VL 2 million
DX May 1 2014
Bio June 5 2014
moderate fibrosis
Start Harvoni 2/5/2015
EOT 4/1/2015
 7/22/2014 alt 186 12/30  64  3/5/15  39
7/22/14  ast 114    12/30.  41  3/5/15  27
Don't know how I got hep C in my 20s I did snort coke a few times.
3/5/15 undetected
4/2/15 less than 15 VL ferrin levels normal
4/9/15 undetected!!
6/24/15 relapse VL 424,000
7/26/16 Started treatment today Harvoni and Ribavirin 24 weeks

Offline Bob V

  • Member
  • Posts: 231
Karen1124
So sorry to hear this :( I know nothing we can say at this point will make the disappointment less, hugs.
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Bob V

  • Member
  • Posts: 231
GLCII
Congrats!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline GLCII

  • Member
  • Posts: 127
GLCII
Congrats!

Thank You Bob V  ;)

I was pretty excited till I read karen1124's post.   :o
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline Pete

  • Member
  • Posts: 110
Failed 12 weeks Harvoni Treatment

Post 4 weeks lab results 06/29/2015 - HCV RNA Quantitative (PCR) 3,661 IU/mL

I recall reading of patients who tested positive at 4 weeks, but end then ended  up clearing the virus.  but this is not even close by the looks of my recent VL, so I've no expectation that will happen here.

Thought I was in after testing undetected at 8 and 12 weeks. Kinda sucks when you can't make the cut at a 97% cure rate...

Not certain of next steps at this time.

Regards,
Pete

Offline Bob V

  • Member
  • Posts: 231
I was pretty excited till I read karen1124's post.
--------
I agree, this thread has lots of up's and down's.
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline Bob V

  • Member
  • Posts: 231
Pete
Sorry but I would wait until the 12wk post lab before losing hope.
Sending good vibes, Bob
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline GLCII

  • Member
  • Posts: 127
Failed 12 weeks Harvoni Treatment

Post 4 weeks lab results 06/29/2015 - HCV RNA Quantitative (PCR) 3,661 IU/mL

I recall reading of patients who tested positive at 4 weeks, but end then ended  up clearing the virus.  but this is not even close by the looks of my recent VL, so I've no expectation that will happen here.

Thought I was in after testing undetected at 8 and 12 weeks. Kinda sucks when you can't make the cut at a 97% cure rate...

Not certain of next steps at this time.

Regards,
Pete

God Damn, I hate seeing these positive results. I had a hard time cracking my RNA results open this morning. My heart races everytime for some weird reason. Believe me when I say it's hard to enjoy and negative when people are showing a positive. This is twice since 8:30 this morning I've read bad news.

Pete

That's still a pretty low number considering that some of the positive results after weeks 4, 8 & 12 are coming back in the 6 & 7 figure range and your's  is just in the 4 area.  I know there's nothing anyone can say to make you feel better and I know how shitty I would feel if I saw that myself but there's still might be hope. I hope! You should still do an 8 week test. 6 week if you can talk your doc in to it.  What are your other labs saying? How's your ALT & AST looking?
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline Pete

  • Member
  • Posts: 110
I really appreciate the replies.. it does help.

I'm not sure why, but LFT's were not performed on this 4 week post tx lab test, only V/L.  I'm still scheduled for more lab tests in 8 weeks according to my nurse, along with another MRI to monitor a liver cyst.

I too started feeling crumby at some point post tx.  Moody, bitchy, intolerant ... seemed to have lost my appetite as well.  Now that I know why, I need to chill it and be more sensitive to those around me.

Best,
pete

Offline Katie

  • Member
  • Posts: 784
I am really sorry to here that for both of you, Karen and Pete.  It is so strange how the cards fall, but know we are all here to support you and you will be successful as they are moving forward with understanding and continuous research.  There are still variables out there that need to be dealt with for 100% cure!

Sending you guys big {{{{HUGS}}}}

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline coloradogirl

  • Member
  • Posts: 70
Karen and Pete,
My heart goes out to you. I hope that an absolute cure will come about. They are getting really close. I think Giliad knows this, and that's why they are advertising their product like crazy. You just hang in there a little bit longer. 
Hugs and prayers!
Colorado Girl
HCV 1a diag 2002
1st tx 2004 null responder
2nd tx 2010 clinical trial relapsed
Last biopsy 2010 F2-F3
Fibrosure inconclusive some parameters out of range
Abdominal Ultrasound 7/2015 - No sign of Cirrhosis
Pretreatment  vl 580,000
Started Harvoni 3/2/2015 EOT: 5/24/2015
4th week 3/27/2015 vl < 5.3 Undetected
8th week 4/23/2015 vl <5.3 Undetected
12 week EOT  5/28/2015 vl <5.3 Undetected
4wk after tx 6/26/2015 vl <5.3 Undetected
12wk after tx 8/19/2015 vl<15 Undetected!!!
I'm Cured! Yes!

Offline Mm

  • Member
  • Posts: 10
 12 weeks Post Harvoni, I have achieved SVR and continued to maintain it.  I an hopeful that undetected remains UND in to the future

Detected in 1990
Treated with Interferon, got sick from tx and not at all better.
Began Harvoni Jan1,2015
UND after month 1 and continued UND for the full 12 weeks.
All blood tests in normal range
Began with viral load of 5.9 million
Fibrosis score 2/3

Offline Bob V

  • Member
  • Posts: 231
Mm
Congrats!
Male 64
Dx hep non AB 1972, Hep C 1991
GT 1A
VL 3.7m (pre tx)
Liver B 1992, unremarkable
Liver ultrasound 2014, normal
Treatment Interferon 90's x2 failed
Started Harvoni 12/08/2014 (12wks)
Finished Harvoni  3/1/15
5wk lab detected <15
8wk lab UND
EOT lab UND!
12wk post lab UND!
24wk post lab UND!
58wk post lab UND!

Offline GLCII

  • Member
  • Posts: 127
Yes! Congratulations Mm  :D

Anyone have any idea when the next set of stats is coming out? Charly8?!
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline GLCII

  • Member
  • Posts: 127
I noticed a few people had questions about spikes in their ALT & AST levels on here. Since ALT & AST are possible indicators of a problem and since these tests usually come back before the Quantative test, can we start adding our ALT & AST levels in to the stats?
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline dragonslayer

  • Member
  • Posts: 873
I dont think Charly8 has posted in over a month.. Hope everything is ok!
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
Saw this on the Harvoni web site

Seems they want to start "The HARVONI Wall"


 http://www.harvoni.com/taking-harvoni/harvoni-wall
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline Katie

  • Member
  • Posts: 784
I checked it out and find it strange they don't want information on those who failed.  Also it would be beneficial if they'd list other side effects since so many had additional problems not listed.  Seems it is just a "Wall" to help sell their product without giving all the information.  I'll check on it again after it has been up for awhile but will pass on signing up now.

Thanks for posting it Lynn. I always appreciate your information.

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline terih

  • Member
  • Posts: 74
Katie, I'm with you on the wondering! It does sort of run true to form from my experience of calling Gilead after my relapse, "Oh sorry bout that." I asked if there was anything they could do for me, nope sorry, bye! I don't mean to sound bitter, but it was a stark contrast to all of the hand holding they provided during treatment! I was truly shocked!

I mean at least let me sign in invisible ink!  ;)
64 yrs. on this fine planet!
diagnosed 1993
Stage 1 cirrhosis
Genotype 1a
12 wks. Harvoni  Relapse late Feb. 2015
Currently treating with Solvaldi/Olysio
The light at the end of the tunnel, is often not a train!

Offline MEG

  • Member
  • Posts: 304
Hi all,

I've missed you. I've been on vacation for a few weeks along with vacationing from the internet ;-)

It's so heartening to hear about so many reaching SVR and painful to hear of others of us who have relapsed....."Hang in there" seem like cold comfort for people like Karen, Pete, terih---but i have no other words. Stay here and get the support and information that this wonderful site provides...hugs.

I was undetectable at 8 weeks post. and will be getting my 12 EOT next week.

We managed to somehow create lives despite HCV, created moments that make life worth living,  and so no matter what results show let's not let this hcv parasite take them and future ones from us....Many hugs
Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.

Offline MEG

  • Member
  • Posts: 304
Hi all,

I've missed you. I've been on vacation for a few weeks along with vacationing from the internet ;-)

It's so heartening to hear about so many reaching SVR and painful to hear of others of us who have relapsed....."Hang in there" seem like cold comfort for people like Karen, Pete, terih---but i have no other words. Stay here and get the support and information that this wonderful site provides...hugs.

I was undetectable at 8 weeks post. and will be getting my 12 EOT next week.

We managed to somehow create lives despite HCV, created moments that make life worth living,  and so no matter what results show let's not let this hcv parasite take them and future ones from us....Many hugs
Geno 1a. IL28B+ with TT polymorphism.
Diagnosed 1993.
Liver Biopsy 1993 --inflammation.
Fibroscan 2014---no fibrosis.
ALT range---60s
AST range---80s.
Platelets: 200K range.
Viral load--2 million range.

Began Harvoni on January 23.
Finished 12 week course on April 19.

May 18---4 week EOT labs:
VL: UNDETECTED.
AST: 23
ALT: 22...........These have not been this low throughout treatment and since my 20s.

12 weeks EOT on July 15---Undetected.

Offline GLCII

  • Member
  • Posts: 127
I dont think Charly8 has posted in over a month.. Hope everything is ok!


On May 29th he posted his 4 week EOT results. His last post was on June 5th. He seemed to be pretty in to doing the stats. I'm hoping nothing has changed since his last test. Has anyone heard from him?

Finally got my 4 week SVR results!

Charly8
1. 4 wk post EOT VL status - Undetected
2. Treatment duration - 12 wks
3. tx naive or experienced - Tx Experienced
4. Genotype (1a or 1b) - 1a
5. F1-F4 fibrosis status (date) - Fibrosure- F3 (Dec 2014), Fibroscan F0-F1 (Mar 2015)
6. Initial VL (date) - 1.05 Mil (Dec 2014)
Pre Tx (VL 12043488) ALT 52/ AST 39
Harvoni Start Date 03/12
2 Week in Tx Results HCV RNA Detected, less than 15 IU/mL. ALT 19 / AST 19
4 Weeks in Tx Results HCV RNA Not detected. ALT 21 / AST 18
12 Week in Tx Results HCV RNA Not detected. ALT 17 / AST 19
--------------------------------------------------------------
Post 12 Week EOT Tx ALT 19/ AST 19 (Undetected)
Post 24 Week EOT Tx ALT 19/ AST 15 (Undetected)

Offline nicole_1234

  • Member
  • Posts: 134
I don't know if I'm the only one who was cautiously optimistic about my 12 wk SVR status. I guess because my doctor is still testing me every 6 weeks. I'll be happy when its over. Just did my 18 week test and still UND. Just wanted to post that in case any other 12 weekers are also worried that their "cure" status is premature. l will post again for my 24.
Genotype 1a
TX interferon/riba 2007 (relapsed)

TX Harvoni 12 week start Dec 3 2014
Starting vl 650,000  ALT 55 AST 63
2 week  vl <15
4 week vl UND
8 week vl UND
12 week EOT ALT 11 AST 18
6 week post tx UND ALT 15 AST 20
12 week post tx UND (CURED!!!!) ALT 11 AST 20
24 week post tx UND ALT 11 AST 18

Offline OO7GUY

  • Member
  • Posts: 27
post 4   RNA "Negative" not detected!!! post 12  RNA "Negative" not detected!!!        SVR ;D
Diagnosed in 08, 1a first TX 08 was Boceprevir, cleared but relapse while still on TX 2nd TX 2010  Telaprevir nonresponder both combination with PEG/riba. 3 TX Harvoni started 1/22/15 doing 12 weeks finished 04/16/15

Offline Momof3

  • Member
  • Posts: 55
12 weeks post harvoni... UNDETECTED
Hep c GT 1a from transfusion at birth 1986
Treatment naive
Stage f0-f1 fibroscan score 2.5kpa
Harvoni started 02/11/2015 8 weeks
Baseline VL 689,594 ALT 35 AST 25
2 weeks ALT 13 AST 16
4 weeks VL <15 detected ALT 12 AST 15
 UNDETECTED  at EOT April 7
4 weeks post Harvoni UNDETECTED ALT 10 AST 14
12 weeks post Harvoni UNDETECTED ALT 8 AST 15
24 weeks post Harvoni UNDETECTED ALT 13 AST 18

CURED!!!!

Offline Katie

  • Member
  • Posts: 784
More GREAT news from 007 and Momo!


YAY!  Way to GO!!!
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline dragonslayer

  • Member
  • Posts: 873
'What a long strange trip its been'.. .Indeed.   Recap of vl test progression:

End of 8 wk treatment:  Detected 29
7.5 wks post treatment:  Detected < 12(LLOQ)
11 wks post treatment:   Undetected

wait for it
wait for it
.
.
.
This just in:
.
24 wks post treatment:  UNDETECTED!   :)   
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Momof3

  • Member
  • Posts: 55
Congrats dragonslayer!!! You are free! Through all the ups and downs, you are cured!
Hep c GT 1a from transfusion at birth 1986
Treatment naive
Stage f0-f1 fibroscan score 2.5kpa
Harvoni started 02/11/2015 8 weeks
Baseline VL 689,594 ALT 35 AST 25
2 weeks ALT 13 AST 16
4 weeks VL <15 detected ALT 12 AST 15
 UNDETECTED  at EOT April 7
4 weeks post Harvoni UNDETECTED ALT 10 AST 14
12 weeks post Harvoni UNDETECTED ALT 8 AST 15
24 weeks post Harvoni UNDETECTED ALT 13 AST 18

CURED!!!!

Offline Katie

  • Member
  • Posts: 784
'What a long strange trip its been'.. .Indeed.   Recap of vl test progression:

This just in:

24 wks post treatment:  UNDETECTED!   :)

You got that right buddy!
 {{{{{HUGS TO YOU}}}} & CONGRATULATIONS!

ENJOY!

Katie

PS  I'm going to miss you.  You helped me through my journey SO much.  Thank you!
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline dragonslayer

  • Member
  • Posts: 873
Thank you guys... But Im not going anywhere!  Ill still be around, correcting the myths and imparting my own brand of scientific reasoning backed up by data.  Im so glad my case has given confidence to others who wound up detected at EOT...  Its the post treatment progression which seems to be more important than an UND at EOT.  So long as the next few tests show a diminishing viral load, then this is inconsistent with a replicating and vital virus..  So long as that load decreases, even if detectable after treatment, odds seem to strongly favor eventual SVR by 12 wks post. If nothing else, this was a game changer for a lot of us.   Thanks to all for their invaluable support.  But this isnt goodbye.. Believe me, Ive gotten too used to things around here to just up and walk away :)  Good luck to those on treatment and those awaiting post treatment results.  All I can say is Harvoni, I bow down to you!!!!!
« Last Edit: July 13, 2015, 05:02:52 pm by dragonslayer »
Paul

DX 2008
Started Harvoni 11/26/14 for 8 wks
Completed 8 wks Harvoni 01/20/15
EOT RNA Quant result:  Detected 29
7.5 wk post tx: Detected < LLOQ(12)
11 wk post tx: UNDETECTED SVR12
24 wk post tx: UNDETECTED SVR24; AST 26; ALT 22; ALP 73
48 wk post tx: UNDETECTED SVR48; AST 18; ALT 18; ALP 70
GT 1a
vl 2.4mil
2008 bpx: Stage&Grade 0
2013 bpx: Stage&Grade: 0-1
IL28B: TT
likely infected early '70s

Offline Lynn K

  • Global Moderator
  • Member
  • Posts: 4,543
  • Get tested, get treated, get cured, fight Hep c!
'
wait for it
wait for it
.
.
.
This just in:
.
24 wks post treatment:  UNDETECTED!   :)

FANTASTIC NEWS PAUL!!!! CONGRATS! Congrats to our other recent dragon slayers 007 and Mom!
Genotype 1a
1978 contracted, 1990 Dx
1995 Intron A failed
2001 Interferon Riba null response
2003 Pegintron Riba trial med null response
2008 F4 Cirrhosis Bx
2014 12 week Sov/Oly relapse
10/14 fibroscan 27 PLT 96
2014 24 weeks Harvoni 15 weeks Riba
5/4/15 EOT not detected, ALT 21, AST 20
4 week post not detected, ALT 26, AST 28
12 week post NOT DETECTED (07/27/15)
ALT 29, AST 27 PLT 92
24 week post NOT DETECTED! (10/19/15)
44 weeks (3/11/16)  fibroscan 33, PLT 111, HCV NOT DETECTED!
I AM FREE!

Offline JoeK9999

  • Member
  • Posts: 88
24 weeks post treatment test results back last week.
UNDETECTED
ALT/AST  24/24

It worked!!!!! I feel great. It took about 5 months after EOT on Harvoni before
side affects wore off. (dizziness mainly).
Diagnosed July 1995 - Genotype 1a
Think I have I had since the early 70's
Prior to Harvoni treatment:
VL 3.8 million AST/ALT 40/56
Mild inflammation, no fibrosis
Treatment naive
 
Started Harvoni 10/23/2014 for 12 weeks
11/20/2014  HCV RNA Qual - Detected
Last Day of Harvoni 01/15/2015
04/08/15 - 12 week post harvoni VL test - Not Detected
07/05/15 - 24 week post harvoni VL test - Not Detected
01/19/16 - 1 Year  post harvoni VL test - Not Detected
AST/ALT 22/22
CURED!!

Offline Karen1124

  • Member
  • Posts: 76
Hey Joe!! CONGRATS to YOU!!! Life is good!! Karen
Geno 1a
VL 2 million
DX May 1 2014
Bio June 5 2014
moderate fibrosis
Start Harvoni 2/5/2015
EOT 4/1/2015
 7/22/2014 alt 186 12/30  64  3/5/15  39
7/22/14  ast 114    12/30.  41  3/5/15  27
Don't know how I got hep C in my 20s I did snort coke a few times.
3/5/15 undetected
4/2/15 less than 15 VL ferrin levels normal
4/9/15 undetected!!
6/24/15 relapse VL 424,000
7/26/16 Started treatment today Harvoni and Ribavirin 24 weeks

Offline JoeK9999

  • Member
  • Posts: 88
Thanks Karen. I am sure you will beat it out soon.
If they gave you the 12 week program instead of the 8 week it probably would have done it. It's a battle in itself just fighting with the doctors and insurance companies.
Diagnosed July 1995 - Genotype 1a
Think I have I had since the early 70's
Prior to Harvoni treatment:
VL 3.8 million AST/ALT 40/56
Mild inflammation, no fibrosis
Treatment naive
 
Started Harvoni 10/23/2014 for 12 weeks
11/20/2014  HCV RNA Qual - Detected
Last Day of Harvoni 01/15/2015
04/08/15 - 12 week post harvoni VL test - Not Detected
07/05/15 - 24 week post harvoni VL test - Not Detected
01/19/16 - 1 Year  post harvoni VL test - Not Detected
AST/ALT 22/22
CURED!!

Offline Katie

  • Member
  • Posts: 784
Thanks Karen. I am sure you will beat it out soon.
If they gave you the 12 week program instead of the 8 week it probably would have done it. It's a battle in itself just fighting with the doctors and insurance companies.

Great news Joe!  Congratulations!  Wooo Hooo!!!

Thanks for adding the 5 month wait to feel good.  I am 4 months out and still have incredible weakness.  All blood work is perfect so how can I be so healthy and feel like crap?  Glad to hear there's a chance to get me back to normal!  Thanks!

Enjoy your Hep Free Life, Joe!

Katie
1 year post treatment blood work done and I am FREE!
GT 1a (4/1/2016)
Dx 2005
VL 2.6 million (fluctuated from 2-16 million during the 9 years)
Started Tx 12/4/2014 for 12 weeks
4 week blood work  Detected 59 IU/mL
EOT Detected <12 IU/mL
7.5 weeks post  Undetected
16 week post Undetected
24 WEEK POST UNDETECTED (I made it)
Waiting to feel good but feeling blessed!
12 month post treatment.  All blood work absolutely perfect! VL, as expected UNDETECTED!

Offline tm

  • Member
  • Posts: 3
I received my 4wk post tx labs today "undetected". Was geno type 1b, 12 wk tx.  First post, although I have been reading for sometime. I was able to get treatment, get the coupon for Harvoni, and only pay $5 total because of all the info on this forum. Thank you. I hope we all get cured!   

Offline JoeK9999

  • Member
  • Posts: 88
Katie,
Sorry you are still feeling bad. Before I started feeling better I went to my Internist
and had the full load of blood tests run including Vitamin B12 and Vitamin D levels
and all was fine too. If you haven't check yet, see if you have low B12 or are anemic.
That could be causing the loss of energy. Just a thought.
I was tired a lot and had the weird dizzy feeling worse when I lied down flat.
Actually it took about 5 1/2 months before it all subsided. All I can think is it was my body taking it's time to heal up after years of hepc.
Good luck with it and hopefully you will be ready to climb a mountain in a few months.
Joe
Diagnosed July 1995 - Genotype 1a
Think I have I had since the early 70's
Prior to Harvoni treatment:
VL 3.8 million AST/ALT 40/56
Mild inflammation, no fibrosis
Treatment naive
 
Started Harvoni 10/23/2014 for 12 weeks
11/20/2014  HCV RNA Qual - Detected
Last Day of Harvoni 01/15/2015
04/08/15 - 12 week post harvoni VL test - Not Detected
07/05/15 - 24 week post harvoni VL test - Not Detected
01/19/16 - 1 Year  post harvoni VL test - Not Detected
AST/ALT 22/22
CURED!!

 


© 2024 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.